PARD6B and CDCA4

Data Source:
BioGRID (two hybrid)

		PARD6B	CDCA4
Description		par-6 family cell polarity regulator beta	cell division cycle associated 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Bicellular Tight Junction Cell Cortex Apical Plasma Membrane Protein-containing Complex Extracellular Exosome	Nucleus Nucleoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Kinase C Binding Protein Binding	Protein Binding Transcription Regulator Activity
	Biological Process	Cell-cell Junction Assembly Centrosome Cycle Establishment Or Maintenance Of Cell Polarity Axonogenesis Regulation Of Cell Migration Cell Division Regulation Of Cellular Localization Protein-containing Complex Assembly Bicellular Tight Junction Assembly	Chromatin-mediated Maintenance Of Transcription
Pathways		Tight junction interactions
Drugs
Diseases
GWAS		Bipolar disorder ( 21771265)	Cerebrospinal fluid t-tau levels ( 29274321) Cerebrospinal fluid t-tau levels in normal cognition ( 29274321) Leukocyte telomere length ( 32109421)
Interacting Genes		33 interacting genes: APP ARAP3 BANP CDC42 CDCA4 CEP76 FRMD6 GMCL1 GOLGA2 HSF2BP HTRA1 MAGOHB PALS1 PARD3 PARD3B PARD6A PNMA1 PRKCG PRKCI PRKCZ RAC1 RASSF3 RHOJ RHOQ SIAH1 TCP10L3 TRIB3 TRIM35 WDR83 YWHAB YWHAH YWHAZ ZSCAN4	25 interacting genes: BFSP2 C1orf109 DOK5 ENKD1 FAM222B FARS2 FNDC11 KAT2B KDM1A KLHL42 MKRN3 PARD6B PRMT6 SEPHS1 SHC3 SUOX SUPT7L SUV39H1 SUV39H2 TCAP TRIM28 TXN2 XPO1 YPEL3 ZNF451
Entrez ID		84612	55038
HPRD ID		18703	13015
Ensembl ID		ENSG00000124171	ENSG00000170779
Uniprot IDs		Q9BYG5	A0A024R6P3 Q9BXL8
PDB IDs
Enriched GO Terms of Interacting Partners?
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