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CARD9 and ZNF250
Data Source:
BioGRID
(two hybrid)
CARD9
ZNF250
Description
caspase recruitment domain family member 9
zinc finger protein 250
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Plasma Membrane
Protein-containing Complex
Nucleus
Molecular Function
Protein Binding
Protein Homodimerization Activity
CARD Domain Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Metal Ion Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Stimulatory C-type Lectin Receptor Signaling Pathway
I-kappaB Kinase/NF-kappaB Signaling
Response To Fungus
Response To Peptidoglycan
Response To Muramyl Dipeptide
Regulation Of Interleukin-2 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Stress-activated MAPK Cascade
Response To Drug
Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Response To Exogenous DsRNA
Innate Immune Response
Positive Regulation Of JNK Cascade
Defense Response To Gram-positive Bacterium
Defense Response To Virus
Regulation Of Transcription By RNA Polymerase II
Pathways
NOD1/2 Signaling Pathway
CLEC7A (Dectin-1) signaling
Generic Transcription Pathway
Drugs
Diseases
Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
GWAS
Acute insulin response (insulin secretion adjusted) (
28490609
)
Ankylosing spondylitis (
23749187
21743469
)
Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) (
26974007
)
Crohn's disease (
28067908
22936669
21102463
)
IgA nephropathy (
25305756
)
Inflammatory bowel disease (
28067908
23128233
)
Joint damage in rheumatoid arthritis (
26498133
)
Large artery stroke (
28265093
)
Monocyte chemoattractant protein-1 levels (
23017229
)
Obesity-related traits (
23251661
)
Pediatric autoimmune diseases (
26301688
)
Ulcerative colitis (
19915572
28067908
20228799
21297633
)
Logical memory (immediate recall) in normal cognition (
29274321
)
Interacting Genes
138 interacting genes:
ABLIM1
AMOTL2
AXIN1
BCL10
BLZF1
C1orf94
C2CD6
CABP2
CARD10
CBX8
CCDC13
CCDC136
CCDC85B
CCDC88B
CCHCR1
CDC37
CDCA7L
CDK2AP1
CEP57L1
CEP70
CSNK2A1
CWF19L2
DAXX
DISC1
DUSP13
DVL2
EFHC2
EIF4A3
EIF4E2
FAM124B
FAM161A
FAM161B
FAM50B
FAM90A1
FOXD4L1
GAS8
GEM
HMBOX1
HOXB5
HSF2BP
IHO1
IKZF3
INO80B
IQCE
KANK2
KCTD9
KIAA0408
KIAA1328
KIF9
KIFC3
KRT15
KRT16
KRT19
KRT31
KRT40
KRT75
KRTAP10-1
KRTAP10-3
KRTAP10-5
KRTAP5-7
L3MBTL2
LENG1
LMO1
LMO3
LNX1
LZTS1
LZTS2
MCRS1
MEOX2
MFAP1
MID2
MYO15B
NECAB2
NTAQ1
PAK5
PBX2
PHC2
PIBF1
PICK1
PKP2
PNMA5
PPP1R18
PRPF18
PSMA4
RBAK
RTP5
SAXO1
SCNM1
SHISA6
SLAIN1
SSX2IP
STMN3
STX11
SUMO1
TASOR2
TCEANC
TCL1A
TEX33
TFIP11
TLE5
TNFAIP1
TNS4
TRIM14
TRIM23
TRIM29
TRIM42
TRIM54
TRIM62
TSGA10IP
TSNAX
UBE2I
UNKL
USH1G
USP15
USP2
VCPKMT
VPS28
YES1
ZBTB16
ZC2HC1C
ZCCHC7
ZGPAT
ZMYM5
ZNF121
ZNF19
ZNF20
ZNF250
ZNF417
ZNF426
ZNF572
ZNF587
ZNF620
ZNF655
ZNF688
ZNF774
ZNF829
ZRANB1
ZZZ3
109 interacting genes:
ANKRD50
APOBEC3C
BEGAIN
CARD10
CARD9
CBY2
CCDC102B
CCDC125
CCDC130
CCDC136
CCDC6
CCDC85B
CDCA7L
CDR2
CDR2L
CEP44
CEP63
DPPA2
DRC3
DVL2
FAM124A
FAM161A
FDXACB1
FHL5
GAS8
GMCL1
GMNN
GNPTAB
GOLGA2
GOLGA6L9
GRAP2
GRIPAP1
GUCD1
HEXIM2
HMBOX1
HOMEZ
HOOK1
HOOK2
HSF2BP
KASH5
KIFC3
KRT31
KRT40
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP4-12
LDOC1
LMO2
LZTS1
LZTS2
MAGOHB
MEOX2
MID2
MTUS2
MYF5
NDEL1
NEXN
NINL
NXF1
PIBF1
PICK1
PLEKHF2
PRDM14
PRPF31
RUBCN
RUNDC3A
SPECC1L
SPRED2
SSX2IP
STX1A
SYNE4
TFF1
TMCC2
TNK1
TNNT1
TNS2
TOP3B
TRAF1
TRAF2
TRIM23
TRIM27
TRIM41
TRIM54
UBE3A
ZBTB43
ZBTB6
ZBTB8A
ZC4H2
ZCCHC13
ZCCHC7
ZFP1
ZNF165
ZNF175
ZNF202
ZNF330
ZNF345
ZNF460
ZNF473
ZNF547
ZNF57
ZNF572
ZNF639
ZNF648
ZNF668
ZNF768
ZNF792
ZNF837
ZRANB1
Entrez ID
64170
58500
HPRD ID
06236
15758
Ensembl ID
ENSG00000187796
ENSG00000196150
Uniprot IDs
A0A024R8F1
Q9H257
B3KNS9
P15622
PDB IDs
6E25
6E26
6E27
6E28
6N2M
6N2P
Enriched GO Terms of Interacting Partners
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