ZNF250 and SPECC1L

Data Source:
BioGRID (two hybrid)

		ZNF250	SPECC1L
Description		zinc finger protein 250	sperm antigen with calponin homology and coiled-coil domains 1 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Microtubule Organizing Center Spindle Gap Junction Actin Cytoskeleton Filamentous Actin
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Cell Cycle Cell Adhesion Actin Cytoskeleton Organization Cell Division
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Logical memory (immediate recall) in normal cognition ( 29274321)	Acne (severe) ( 24927181 30542056) Coronary artery disease ( 32469254 29212778) Mean reticulocyte volume ( 32888494) Severity of nausea and vomiting of pregnancy ( 29563502)
Interacting Genes		109 interacting genes: ANKRD50 APOBEC3C BEGAIN CARD10 CARD9 CBY2 CCDC102B CCDC125 CCDC130 CCDC136 CCDC6 CCDC85B CDCA7L CDR2 CDR2L CEP44 CEP63 DPPA2 DRC3 DVL2 FAM124A FAM161A FDXACB1 FHL5 GAS8 GMCL1 GMNN GNPTAB GOLGA2 GOLGA6L9 GRAP2 GRIPAP1 GUCD1 HEXIM2 HMBOX1 HOMEZ HOOK1 HOOK2 HSF2BP KASH5 KIFC3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP4-12 LDOC1 LMO2 LZTS1 LZTS2 MAGOHB MEOX2 MID2 MTUS2 MYF5 NDEL1 NEXN NINL NXF1 PIBF1 PICK1 PLEKHF2 PRDM14 PRPF31 RUBCN RUNDC3A SPECC1L SPRED2 SSX2IP STX1A SYNE4 TFF1 TMCC2 TNK1 TNNT1 TNS2 TOP3B TRAF1 TRAF2 TRIM23 TRIM27 TRIM41 TRIM54 UBE3A ZBTB43 ZBTB6 ZBTB8A ZC4H2 ZCCHC13 ZCCHC7 ZFP1 ZNF165 ZNF175 ZNF202 ZNF330 ZNF345 ZNF460 ZNF473 ZNF547 ZNF57 ZNF572 ZNF639 ZNF648 ZNF668 ZNF768 ZNF792 ZNF837 ZRANB1	11 interacting genes: APC ECPAS EFCAB3 ELOA GLIS2 PPP1R12C SNW1 UBC UBE2I ZFHX3 ZNF250
Entrez ID		58500	23384
HPRD ID		15758	11080
Ensembl ID		ENSG00000196150	ENSG00000100014
Uniprot IDs		B3KNS9 P15622	B2RMV2 Q69YQ0
PDB IDs
Enriched GO Terms of Interacting Partners?
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