ZNF250 and GNPTAB

Data Source:
BioGRID (two hybrid)

		ZNF250	GNPTAB
Description		zinc finger protein 250	N-acetylglucosamine-1-phosphate transferase subunits alpha and beta
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Golgi Membrane Golgi Apparatus Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Metal Ion Binding Sequence-specific Double-stranded DNA Binding	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase Activity Calcium Ion Binding Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Lysosome Organization N-glycan Processing To Lysosome Secretion Of Lysosomal Enzymes Carbohydrate Phosphorylation
Pathways		Generic Transcription Pathway
Drugs
Diseases			Mucolipidosis II and III, including: Mucolipidosis II / I-cell disease; Mucolipidosis III A / Pseudo-Hurler polydystrophy; Mucolipidosis III C
GWAS		Logical memory (immediate recall) in normal cognition ( 29274321)	Blood protein levels ( 29875488 28240269) Bone mineral density (total hip) ( 29883787) Brain morphology (MOSTest) ( 32665545)
Interacting Genes		109 interacting genes: ANKRD50 APOBEC3C BEGAIN CARD10 CARD9 CBY2 CCDC102B CCDC125 CCDC130 CCDC136 CCDC6 CCDC85B CDCA7L CDR2 CDR2L CEP44 CEP63 DPPA2 DRC3 DVL2 FAM124A FAM161A FDXACB1 FHL5 GAS8 GMCL1 GMNN GNPTAB GOLGA2 GOLGA6L9 GRAP2 GRIPAP1 GUCD1 HEXIM2 HMBOX1 HOMEZ HOOK1 HOOK2 HSF2BP KASH5 KIFC3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP4-12 LDOC1 LMO2 LZTS1 LZTS2 MAGOHB MEOX2 MID2 MTUS2 MYF5 NDEL1 NEXN NINL NXF1 PIBF1 PICK1 PLEKHF2 PRDM14 PRPF31 RUBCN RUNDC3A SPECC1L SPRED2 SSX2IP STX1A SYNE4 TFF1 TMCC2 TNK1 TNNT1 TNS2 TOP3B TRAF1 TRAF2 TRIM23 TRIM27 TRIM41 TRIM54 UBE3A ZBTB43 ZBTB6 ZBTB8A ZC4H2 ZCCHC13 ZCCHC7 ZFP1 ZNF165 ZNF175 ZNF202 ZNF330 ZNF345 ZNF460 ZNF473 ZNF547 ZNF57 ZNF572 ZNF639 ZNF648 ZNF668 ZNF768 ZNF792 ZNF837 ZRANB1	8 interacting genes: AEN APP DISC1 FAM90A1 MAPK1 PSMA1 STAMBPL1 ZNF250
Entrez ID		58500	79158
HPRD ID		15758	11350
Ensembl ID		ENSG00000196150	ENSG00000111670
Uniprot IDs		B3KNS9 P15622	Q3T906
PDB IDs			2N6D
Enriched GO Terms of Interacting Partners?
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