BDKRB1 and MBOAT7

Data Source:
BioGRID (two hybrid)

		BDKRB1	MBOAT7
Description		bradykinin receptor B1	membrane bound O-acyltransferase domain containing 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Mitochondria-associated Endoplasmic Reticulum Membrane
	Molecular Function	G Protein-coupled Receptor Activity Bradykinin Receptor Activity Protein Binding Peptide Binding	1-acylglycerol-3-phosphate O-acyltransferase Activity Protein Binding O-acyltransferase Activity Transferase Activity, Transferring Acyl Groups 2-acylglycerol-3-phosphate O-acyltransferase Activity Lysophospholipid Acyltransferase Activity
	Biological Process	Negative Regulation Of Protein Phosphorylation Positive Regulation Of Leukocyte Migration Inflammatory Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Response To Mechanical Stimulus Cell Migration Sensory Perception Of Pain Negative Regulation Of Cell Growth Response To Lipopolysaccharide Negative Regulation Of Blood Pressure Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol	Phosphatidylinositol Biosynthetic Process Ventricular System Development Layer Formation In Cerebral Cortex Lipid Modification Phosphatidylinositol Acyl-chain Remodeling Phosphatidylcholine Acyl-chain Remodeling Regulation Of Triglyceride Metabolic Process
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events	Acyl chain remodelling of PI
Drugs		Ramipril Captopril Zinc Enalaprilat Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Metabolite levels ( 23823483)	Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Cirrhosis (alcohol related) ( 26482880) Obesity-related traits ( 23251661) Phosphatidylinositol levels ( 31551469)
Interacting Genes		32 interacting genes: C1orf43 CERS1 DNAJB1 GABBR1 GNAQ GRIN1 HHATL HILPDA HTT INSIG1 LAPTM4B LRRC4C MBOAT7 MDC1 NAGPA NAP1L4 NDFIP1 NF2 OAZ2 RAE1 RETREG1 RTN4 SLC25A28 SLC39A14 SLC44A2 SLC6A8 TMEM42 TMX2 TRAM1L1 TRAT1 UQCRC1 ZNF22	6 interacting genes: ADRA1A BDKRB1 MAPK6 STING1 UBC UNC93B1
Entrez ID		623	79143
HPRD ID		02639	06925
Ensembl ID		ENSG00000100739	ENSG00000125505
Uniprot IDs		P46663	Q96N66
PDB IDs
Enriched GO Terms of Interacting Partners?
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