BDKRB1 and SLC6A8

Data Source:
BioGRID (two hybrid)

		BDKRB1	SLC6A8
Description		bradykinin receptor B1	solute carrier family 6 member 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Activity Bradykinin Receptor Activity Protein Binding Peptide Binding	Molecular_function Creatine Transmembrane Transporter Activity Creatine:sodium Symporter Activity
	Biological Process	Negative Regulation Of Protein Phosphorylation Positive Regulation Of Leukocyte Migration Inflammatory Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Response To Mechanical Stimulus Cell Migration Sensory Perception Of Pain Negative Regulation Of Cell Growth Response To Lipopolysaccharide Negative Regulation Of Blood Pressure Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol	Creatine Metabolic Process Neurotransmitter Transport Muscle Contraction Creatine Transmembrane Transport Sodium Ion Transmembrane Transport Nitrogen Compound Transport
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events	Creatine metabolism
Drugs		Ramipril Captopril Zinc Enalaprilat Zinc acetate Zinc chloride Zinc sulfate, unspecified form	Creatine Phosphocreatine
Diseases			Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS) Non-syndromic X-linked mental retardation Creatine deficiency syndrome, including: Arginine:glycine amidinotransferase deficiency (AGAT deficiency); Guanidinoacetate methyltransferase deficiency (GAMT deficiency); X-linked creatine deficiency syndrome (XL-CDS)
GWAS		Metabolite levels ( 23823483)
Interacting Genes		32 interacting genes: C1orf43 CERS1 DNAJB1 GABBR1 GNAQ GRIN1 HHATL HILPDA HTT INSIG1 LAPTM4B LRRC4C MBOAT7 MDC1 NAGPA NAP1L4 NDFIP1 NF2 OAZ2 RAE1 RETREG1 RTN4 SLC25A28 SLC39A14 SLC44A2 SLC6A8 TMEM42 TMX2 TRAM1L1 TRAT1 UQCRC1 ZNF22	3 interacting genes: BDKRB1 CD59 CHRM5
Entrez ID		623	6535
HPRD ID		02639	02073
Ensembl ID		ENSG00000100739	ENSG00000130821
Uniprot IDs		P46663	P48029 Q59EV7 X5D9C4
PDB IDs
Enriched GO Terms of Interacting Partners?
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