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RANBP2 and CDCA8
Data Source:
BioGRID
(affinity chromatography technology, enzymatic study)
RANBP2
CDCA8
Description
RAN binding protein 2
cell division cycle associated 8
Image
GO Annotations
Cellular Component
Nuclear Envelope
Annulate Lamellae
Nuclear Pore
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Membrane
Nuclear Membrane
Nuclear Inclusion Body
Intracellular Membrane-bounded Organelle
Host Cell
Nuclear Pore Cytoplasmic Filaments
Nuclear Pore Nuclear Basket
Cytoplasmic Periphery Of The Nuclear Pore Complex
Chromosome, Centromeric Region
Nucleoplasm
Nucleolus
Cytosol
Chromocenter
Midbody
Chromosome Passenger Complex
Protein-containing Complex
Intercellular Bridge
Spindle Midzone
Molecular Function
RNA Binding
Peptidyl-prolyl Cis-trans Isomerase Activity
GTPase Activator Activity
Protein Binding
Cyclosporin A Binding
SUMO Transferase Activity
Small GTPase Binding
Protein-containing Complex Binding
Metal Ion Binding
Protein Binding
Biological Process
Protein Peptidyl-prolyl Isomerization
Response To Amphetamine
Regulation Of Glycolytic Process
Regulation Of Gluconeogenesis
MRNA Export From Nucleus
TRNA Export From Nucleus
Protein Folding
NLS-bearing Protein Import Into Nucleus
Viral Process
Protein Sumoylation
Viral Transcription
Positive Regulation Of Glucokinase Activity
Positive Regulation Of GTPase Activity
Centrosome Localization
Regulation Of Gene Silencing By MiRNA
Intracellular Transport Of Virus
Regulation Of Cellular Response To Heat
Mitotic Sister Chromatid Segregation
Mitotic Metaphase Plate Congression
Chromosome Organization
Cell Division
Pathways
ISG15 antiviral mechanism
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
snRNP Assembly
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
RHO GTPases Activate Formins
tRNA processing in the nucleus
Mitotic Prometaphase
HCMV Early Events
HCMV Late Events
EML4 and NUDC in mitotic spindle formation
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
SUMOylation of DNA replication proteins
RHO GTPases Activate Formins
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Attention deficit hyperactivity disorder (
29325848
)
Beard thickness (
26926045
)
Monobrow thickness (
26926045
)
Scalp hair shape (
26926045
)
Axial length (
24144296
)
Eyebrow thickness (
26926045
)
Interacting Genes
38 interacting genes:
AKAP13
ARID4B
CALM1
CDCA8
CUL1
FHOD1
HDAC4
IFT140
IPO5
KPNA1
KPNA2
KPNB1
LRPAP1
MAP2K7
MDM2
MYBPC2
NFX1
NUP62
NXF1
OPN1LW
OPN1MW
PDLIM3
PRKN
PTEN
RAN
RANGAP1
SENP1
SP100
SUMO1
SUMO2
TAF1
TNPO1
TOP2B
UBE2I
UBTD1
WAS
XPO1
XPOT
26 interacting genes:
AURKB
BIRC5
EMILIN1
FBXO17
GYS1
H3C14
HLA-DRB3
HMBOX1
INCENP
MAPKAPK5
NEK3
NKAPD1
NTAQ1
PIAS2
PIH1D2
RANBP2
RPRD1B
SENP3
SET
SGO1
SGO2
SNAPC5
SPANXN2
TTK
UBE2I
ZNF277
Entrez ID
5903
55143
HPRD ID
03111
13017
Ensembl ID
ENSG00000153201
ENSG00000134690
Uniprot IDs
P49792
Q53HL2
PDB IDs
1RRP
1XKE
1Z5S
2LAS
3UIN
3UIO
3UIP
4GA0
4I9Y
4L6E
4LQW
5CLL
5CLQ
2KDD
2QFA
2RAW
2RAX
6YIE
6YIF
6YIH
Enriched GO Terms of Interacting Partners
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