CDCA8 and ZNF277

Data Source:
BioGRID (two hybrid)

		CDCA8	ZNF277
Description		cell division cycle associated 8	zinc finger protein 277
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Nucleoplasm Nucleolus Cytosol Chromocenter Midbody Chromosome Passenger Complex Protein-containing Complex Intercellular Bridge Spindle Midzone	Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Mitotic Sister Chromatid Segregation Mitotic Metaphase Plate Congression Chromosome Organization Cell Division	Cellular Response To Hydrogen Peroxide Regulation Of Cellular Senescence
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA replication proteins RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Axial length ( 24144296) Eyebrow thickness ( 26926045)	Breast size ( 22747683) Early-onset Parkinson's disease ( 28256260) Refractive error ( 32231278)
Interacting Genes		26 interacting genes: AURKB BIRC5 EMILIN1 FBXO17 GYS1 H3C14 HLA-DRB3 HMBOX1 INCENP MAPKAPK5 NEK3 NKAPD1 NTAQ1 PIAS2 PIH1D2 RANBP2 RPRD1B SENP3 SET SGO1 SGO2 SNAPC5 SPANXN2 TTK UBE2I ZNF277	9 interacting genes: CDCA8 COIL DDB1 GNGT1 MBD3 NUTM1 RPP14 ZBTB7B ZNF768
Entrez ID		55143	11179
HPRD ID		13017	05680
Ensembl ID		ENSG00000134690	ENSG00000198839
Uniprot IDs		Q53HL2	Q9NRM2
PDB IDs		2KDD 2QFA 2RAW 2RAX 6YIE 6YIF 6YIH
Enriched GO Terms of Interacting Partners?
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