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PTPRS and CHD3
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
PTPRS
CHD3
Description
protein tyrosine phosphatase receptor type S
chromodomain helicase DNA binding protein 3
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Plasma Membrane
Integral Component Of Plasma Membrane
Integral Component Of Synaptic Vesicle Membrane
Axon
Growth Cone
Perikaryon
Extracellular Exosome
Schaffer Collateral - CA1 Synapse
Glutamatergic Synapse
Integral Component Of Presynaptic Membrane
Integral Component Of Postsynaptic Density Membrane
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Centrosome
NuRD Complex
PML Body
Centriolar Satellite
Molecular Function
Phosphoprotein Phosphatase Activity
Protein Tyrosine Phosphatase Activity
Protein Binding
Heparin Binding
Chondroitin Sulfate Binding
Heparan Sulfate Proteoglycan Binding
Transcription Regulatory Region Sequence-specific DNA Binding
DNA Binding
DNA Helicase Activity
RNA Binding
Helicase Activity
Protein Binding
ATP Binding
Zinc Ion Binding
ATPase Activity
Double-stranded DNA Helicase Activity
Nucleosome-dependent ATPase Activity
Biological Process
Protein Dephosphorylation
Negative Regulation Of Neuron Projection Development
Spinal Cord Development
Cerebellum Development
Hippocampus Development
Cerebral Cortex Development
Corpus Callosum Development
Negative Regulation Of Axon Extension
Negative Regulation Of Interferon-alpha Production
Negative Regulation Of Interferon-beta Production
Negative Regulation Of Toll-like Receptor 9 Signaling Pathway
Peptidyl-tyrosine Dephosphorylation
Negative Regulation Of Collateral Sprouting
Negative Regulation Of Axon Regeneration
Modulation Of Chemical Synaptic Transmission
Negative Regulation Of Dendritic Spine Development
Establishment Of Endothelial Intestinal Barrier
Regulation Of Postsynaptic Density Assembly
Synaptic Membrane Adhesion
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Assembly Or Disassembly
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Spindle Organization
Centrosome Cycle
DNA Duplex Unwinding
ATP-dependent Chromatin Remodeling
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
ECM proteoglycans
Receptor-type tyrosine-protein phosphatases
Synaptic adhesion-like molecules
Signaling by NTRK3 (TRKC)
HDACs deacetylate histones
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
SUMOylation of chromatin organization proteins
Regulation of TP53 Activity through Acetylation
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Potential therapeutics for SARS
Drugs
Alendronic acid
Etidronic acid
Diseases
GWAS
Thyroid stimulating hormone levels (
32769997
)
Type 2 diabetes (
30297969
)
Waist-hip ratio (
28552196
)
Ischemic stroke (
26089329
)
Macular thickness (
30535121
)
Prostate cancer (
29892016
)
Refractive error (
32231278
)
Stroke (
26089329
)
Interacting Genes
27 interacting genes:
CEP126
CHD3
EEF1G
EGFR
FEZ1
GPC2
GPC3
GPC6
KAT5
MOB4
PFN2
PPFIA1
PPFIA2
PPFIA3
PTN
PTPRA
PTPRD
PTPRE
PTPRM
PTPRN
RAB35
SETDB1
SLITRK1
TUBB2A
UBR1
UNC119
UTP14A
96 interacting genes:
ACTR1B
ADH5
AIMP2
ATP5IF1
BARD1
BCL6
BHLHE40
C4orf17
CASP6
CASP8
CPE
CRCT1
CREB1
CREBBP
CSTF2
CTBP1
CTTN
ENTR1
FABP4
FBP2
FUBP1
GADD45A
GIT1
GPS2
GSK3B
H3C1
HABP4
HSD17B10
HSPH1
HTT
IK
IKZF1
IKZF3
IMMT
IVNS1ABP
KIF15
KPNA2
KPNB1
LRIF1
LUC7L2
MAFG
MAN2A2
MX1
MYB
NEFL
NR1H2
NR4A1
PAICS
PCMT1
PIAS4
PLK4
PRG2
PRPF40A
PSME1
PTN
PTPRS
PUF60
RAD51
RETREG2
RGS2
RIF1
RPL29
SAFB
SAT1
SATB1
SERBP1
SERF2
SGSM2
SIRT6
SKIL
SLC27A6
SPOP
SRRT
SUMO1
SUMO2
TAL1
TCERG1
THOC7
TNFRSF14
TNNT1
TP53
TP73
TRIM28
TRIM54
TSC22D1
TSPAN6
TTR
TXNDC9
UBA3
UBC
UBE2I
UROD
VIM
XRCC4
YAE1
ZHX1
Entrez ID
5802
1107
HPRD ID
03344
09071
Ensembl ID
ENSG00000105426
ENSG00000170004
Uniprot IDs
Q13332
Q59FX6
Q8NHS7
B3KWV4
Q12873
Q2TAZ1
PDB IDs
2FH7
2YD2
2YD3
2YD9
4BPC
4PBX
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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