NUP133 and NUP107

Data Source:
HPRD (in vivo, in vitro)

		NUP133	NUP107
Description		nucleoporin 133	nucleoporin 107
Image
GO Annotations	Cellular Component	Condensed Chromosome Kinetochore Condensed Chromosome Outer Kinetochore Nuclear Envelope Nuclear Pore Cytosol Membrane Nuclear Pore Outer Ring Nuclear Membrane Host Cell	Kinetochore Condensed Chromosome Kinetochore Nuclear Envelope Nuclear Pore Cytosol Membrane Nuclear Pore Outer Ring Nuclear Membrane Nuclear Periphery Host Cell
	Molecular Function	Protein Binding Structural Constituent Of Nuclear Pore	Protein Binding Structural Constituent Of Nuclear Pore
	Biological Process	Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Regulation Of Glycolytic Process MRNA Export From Nucleus TRNA Export From Nucleus Protein Import Into Nucleus Nuclear Pore Organization Viral Process Protein Sumoylation Poly(A)+ MRNA Export From Nucleus Viral Transcription Neural Tube Development Neurogenesis Paraxial Mesoderm Development Regulation Of Gene Silencing By MiRNA Somite Development Nephron Development Intracellular Transport Of Virus Regulation Of Cellular Response To Heat	Posttranscriptional Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Regulation Of Glycolytic Process Regulation Of Transcription, DNA-templated MRNA Export From Nucleus TRNA Export From Nucleus Protein Import Into Nucleus Female Gonad Development Viral Process Protein Sumoylation Viral Transcription Nuclear Pore Complex Assembly Regulation Of Gene Silencing By MiRNA Nephron Development Intracellular Transport Of Virus Regulation Of Cellular Response To Heat
Pathways		ISG15 antiviral mechanism Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) RHO GTPases Activate Formins tRNA processing in the nucleus Mitotic Prometaphase HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation EML4 and NUDC in mitotic spindle formation	ISG15 antiviral mechanism Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) RHO GTPases Activate Formins tRNA processing in the nucleus Mitotic Prometaphase HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Type 2 diabetes ( 32499647)	White blood cell count ( 20139978)
Interacting Genes		4 interacting genes: CENPF NUP107 NUP98 TCAP	3 interacting genes: NUP133 NUP214 SUMO2
Entrez ID		55746	57122
HPRD ID		06354	06356
Ensembl ID		ENSG00000069248	ENSG00000111581
Uniprot IDs		Q8WUM0	P57740
PDB IDs		1XKS 3CQC 3CQG 3I4R 5A9Q	3CQC 3CQG 3I4R 5A9Q
Enriched GO Terms of Interacting Partners?
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