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NUP133 and CENPF
Data Source:
HPRD
(two hybrid, in vivo)
NUP133
CENPF
Description
nucleoporin 133
centromere protein F
Image
No pdb structure
GO Annotations
Cellular Component
Condensed Chromosome Kinetochore
Condensed Chromosome Outer Kinetochore
Nuclear Envelope
Nuclear Pore
Cytosol
Membrane
Nuclear Pore Outer Ring
Nuclear Membrane
Host Cell
Chromosome, Centromeric Region
Kinetochore
Chromatin
Spindle Pole
Condensed Chromosome Outer Kinetochore
Nucleus
Nuclear Envelope
Nucleoplasm
Cytoplasm
Centrosome
Spindle
Cytosol
Axoneme
Nuclear Matrix
Midbody
Ciliary Basal Body
Pronucleus
Perinuclear Region Of Cytoplasm
Ciliary Transition Fiber
Molecular Function
Protein Binding
Structural Constituent Of Nuclear Pore
Chromatin Binding
Protein Binding
Microtubule Binding
Protein C-terminus Binding
Transcription Factor Binding
Protein Homodimerization Activity
Dynein Complex Binding
Biological Process
Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery
Regulation Of Glycolytic Process
MRNA Export From Nucleus
TRNA Export From Nucleus
Protein Import Into Nucleus
Nuclear Pore Organization
Viral Process
Protein Sumoylation
Poly(A)+ MRNA Export From Nucleus
Viral Transcription
Neural Tube Development
Neurogenesis
Paraxial Mesoderm Development
Regulation Of Gene Silencing By MiRNA
Somite Development
Nephron Development
Intracellular Transport Of Virus
Regulation Of Cellular Response To Heat
Mitotic Cell Cycle
Kidney Development
Chromosome Segregation
Mitotic Spindle Assembly Checkpoint
Muscle Organ Development
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Protein Transport
Regulation Of Striated Muscle Tissue Development
Ventricular System Development
Cell Differentiation
Response To Drug
Negative Regulation Of Transcription, DNA-templated
Cell Division
Metaphase Plate Congression
Kinetochore Assembly
Regulation Of Cell Cycle
DNA Biosynthetic Process
Pathways
ISG15 antiviral mechanism
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
snRNP Assembly
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
RHO GTPases Activate Formins
tRNA processing in the nucleus
Mitotic Prometaphase
HCMV Early Events
HCMV Late Events
Postmitotic nuclear pore complex (NPC) reformation
Postmitotic nuclear pore complex (NPC) reformation
EML4 and NUDC in mitotic spindle formation
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Polo-like kinase mediated events
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Type 2 diabetes (
32499647
)
Age-related cognitive decline (memory) (slope of z-scores) (
30954325
)
Lung function (FVC) (
30061609
)
Response to antineoplastic agents (
21659360
)
Serum immune biomarker levels (
32066700
)
Interacting Genes
4 interacting genes:
CENPF
NUP107
NUP98
TCAP
10 interacting genes:
BRAP
CENPE
CHMP2B
FNTA
FNTB
NDEL1
NUP133
SNAP25
SVIL
TOP3B
Entrez ID
55746
1063
HPRD ID
06354
02582
Ensembl ID
ENSG00000069248
ENSG00000117724
Uniprot IDs
Q8WUM0
P49454
PDB IDs
1XKS
3CQC
3CQG
3I4R
5A9Q
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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