PTPA and KISS1R

Data Source:
BioGRID (pull down)

		PTPA	KISS1R
Description		protein phosphatase 2 phosphatase activator	KISS1 receptor
Image			No pdb structure
GO Annotations	Cellular Component	Protein Phosphatase Type 2A Complex Nucleus Nucleoplasm Cytoplasm Calcium Channel Complex Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Cilium Cell Surface Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Signaling Receptor Binding Protein Binding ATP Binding Protein Tyrosine Phosphatase Activator Activity ATPase Activity Protein Phosphatase Regulator Activity Protein Homodimerization Activity Protein Phosphatase 2A Binding	Protein Binding Neuropeptide Receptor Activity G Protein-coupled Peptide Receptor Activity
	Biological Process	Protein Peptidyl-prolyl Isomerization Mitotic Spindle Organization Negative Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Protein Dephosphorylation Positive Regulation Of Apoptotic Process Regulation Of Phosphoprotein Phosphatase Activity	G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway
Pathways			Peptide ligand-binding receptors G alpha (q) signalling events
Drugs			ANZ-100
Diseases			Precocious puberty, including: Central precocious puberty (CEPREPU); Familial male precocious puberty (FMPP) Hypogonadotropic hypogonadism; Kallmann syndrome (KAL)
GWAS			Menopause (age at onset) ( 26414677) Sweet taste preference ( 32572145)
Interacting Genes		28 interacting genes: AKT1 AMOT APP AURKB CCDC125 CCNE1 CCNG1 CCNG2 CSNK2A1 CYLD DTD1 EIF4EBP1 F3 FOXO3 GRIN3A H2AX HDAC4 KISS1R MAPT MID1 NIF3L1 PPP2R1A PPP2R3A PRKCB RACGAP1 SPG21 SRC SULT4A1	3 interacting genes: KISS1 PPP2CA PTPA
Entrez ID		5524	84634
HPRD ID		02858	09167
Ensembl ID		ENSG00000119383	ENSG00000116014
Uniprot IDs		B4DZF8 F6WIT2 Q15257	Q969F8 U3KQ86
PDB IDs		2G62 2HV6 2HV7 2IXM 4LAC 4NY3
Enriched GO Terms of Interacting Partners?
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