PTPA and CCDC125

Data Source:
BioGRID (two hybrid)

		PTPA	CCDC125
Description		protein phosphatase 2 phosphatase activator	coiled-coil domain containing 125
Image			No pdb structure
GO Annotations	Cellular Component	Protein Phosphatase Type 2A Complex Nucleus Nucleoplasm Cytoplasm Calcium Channel Complex Extracellular Exosome	Cytoplasm
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Signaling Receptor Binding Protein Binding ATP Binding Protein Tyrosine Phosphatase Activator Activity ATPase Activity Protein Phosphatase Regulator Activity Protein Homodimerization Activity Protein Phosphatase 2A Binding	Molecular_function Protein Binding Identical Protein Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization Mitotic Spindle Organization Negative Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Protein Dephosphorylation Positive Regulation Of Apoptotic Process Regulation Of Phosphoprotein Phosphatase Activity	Negative Regulation Of Rho Protein Signal Transduction Activation Of GTPase Activity Negative Regulation Of Cell Motility
Pathways
Drugs
Diseases
GWAS			Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Lymphocyte percentage of white cells ( 32888494) Monocyte percentage of white cells ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494 27863252) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252)
Interacting Genes		28 interacting genes: AKT1 AMOT APP AURKB CCDC125 CCNE1 CCNG1 CCNG2 CSNK2A1 CYLD DTD1 EIF4EBP1 F3 FOXO3 GRIN3A H2AX HDAC4 KISS1R MAPT MID1 NIF3L1 PPP2R1A PPP2R3A PRKCB RACGAP1 SPG21 SRC SULT4A1	64 interacting genes: BMP7 C1orf109 C21orf58 C22orf15 C4orf45 CCNG1 CDC23 CDK18 CEP95 EIF3D FAM107A FAM161A FAM161B FAM214B FAM47B FLYWCH1 GAS8 GEM HAPLN2 HDAC4 KAT5 KIF9 KRTAP13-2 LCE2C MYH1 NEBL NSD1 NSMF OTOS PKP2 PRPF3 PTPA RAB2A RIPOR3 SFN SNW1 STX11 TCHP TEAD4 TRIM14 TSGA10IP UACA YWHAE YWHAH YWHAQ YWHAZ ZFP1 ZFYVE26 ZNF165 ZNF230 ZNF250 ZNF32 ZNF337 ZNF343 ZNF417 ZNF436 ZNF552 ZNF557 ZNF564 ZNF587 ZNF764 ZNF792 ZNF837 ZNF883
Entrez ID		5524	202243
HPRD ID		02858	13774
Ensembl ID		ENSG00000119383	ENSG00000183323
Uniprot IDs		B4DZF8 F6WIT2 Q15257	B4DSR1 Q2HJ12 Q86Z20
PDB IDs		2G62 2HV6 2HV7 2IXM 4LAC 4NY3
Enriched GO Terms of Interacting Partners?
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