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MAGOHB and DVL2
Data Source:
BioGRID
(two hybrid)
MAGOHB
DVL2
Description
mago homolog B, exon junction complex subunit
dishevelled segment polarity protein 2
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Exon-exon Junction Complex
Neuronal Cell Body
U2-type Precatalytic Spliceosome
U2-type Catalytic Step 1 Spliceosome
Catalytic Step 2 Spliceosome
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Aggresome
Lateral Plasma Membrane
Nuclear Body
Cytoplasmic Vesicle
Apical Part Of Cell
Clathrin-coated Endocytic Vesicle
Molecular Function
RNA Binding
Protein Binding
Frizzled Binding
Protein Binding
Protein Kinase Binding
Protein Domain Specific Binding
Protein-macromolecule Adaptor Activity
Small GTPase Binding
Identical Protein Binding
Protein Self-association
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
MRNA Splicing, Via Spliceosome
RNA Export From Nucleus
MRNA Export From Nucleus
RNA Splicing
MRNA 3'-end Processing
Neural Tube Closure
Positive Regulation Of Protein Phosphorylation
Outflow Tract Morphogenesis
Regulation Of Transcription, DNA-templated
Segment Specification
Heart Development
Convergent Extension Involved In Neural Plate Elongation
Cellular Protein Localization
Hippo Signaling
Non-canonical Wnt Signaling Pathway
Positive Regulation Of JUN Kinase Activity
Positive Regulation Of GTPase Activity
Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of DNA-binding Transcription Factor Activity
Canonical Wnt Signaling Pathway
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Membrane Organization
Positive Regulation Of Protein Tyrosine Kinase Activity
Negative Regulation Of Canonical Wnt Signaling Pathway
Cochlea Morphogenesis
Planar Cell Polarity Pathway Involved In Neural Tube Closure
Positive Regulation Of Neuron Projection Arborization
Beta-catenin Destruction Complex Disassembly
Pathways
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
Regulation of expression of SLITs and ROBOs
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
TCF dependent signaling in response to WNT
WNT mediated activation of DVL
Signaling by Hippo
PCP/CE pathway
PCP/CE pathway
Asymmetric localization of PCP proteins
Degradation of DVL
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Disassembly of the destruction complex and recruitment of AXIN to the membrane
WNT5A-dependent internalization of FZD4
Negative regulation of TCF-dependent signaling by DVL-interacting proteins
RHO GTPases Activate Formins
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
WNT5:FZD7-mediated leishmania damping
WNT5:FZD7-mediated leishmania damping
Drugs
Diseases
GWAS
Metabolite levels (
31628463
)
Metabolite levels (small molecules and protein measures) (
27005778
)
Interacting Genes
73 interacting genes:
ADAMTSL4
AMOTL2
BEND7
C18orf54
CALCOCO2
CARD10
CCDC102B
CCDC106
CCDC33
DVL2
DVL3
EFHC2
FHL5
FXR1
GNPDA2
GOLGA2
GPANK1
HMG20A
HSF2BP
IHO1
IKZF1
IKZF3
INCA1
KRT40
KRT75
KRTAP1-1
KRTAP13-2
MID2
NDUFB7
PARD6B
PAX7
PBX4
PKP2
PRPH
PRPSAP1
PTPN21
RBAK
RBM8A
RBMX
REL
RUNDC3A
SNW1
SPATA6
SPDYE4
STX11
TADA2A
TCF4
TERF2
TERF2IP
THAP7
TLE5
TRA2A
TRA2B
TRIM27
TRIM42
YWHAG
ZBTB10
ZBTB42
ZFP14
ZFYVE1
ZNF19
ZNF250
ZNF398
ZNF426
ZNF438
ZNF446
ZNF449
ZNF547
ZNF566
ZNF57
ZNF620
ZNF774
ZNF835
103 interacting genes:
ABL1
AKAP9
AP1M1
AP2M1
ARHGEF39
ARR3
ARRB1
ARRB2
ATN1
AXIN1
BAG3
BAHD1
BCL6
BEND7
BYSL
CARD9
CCDC33
CPSF7
CSNK1E
CTBP2
DAAM1
DCUN1D1
DDI1
DPPA2
DYNLT1
EIF1B
ELOA2
ENKD1
FAM161A
FAM90A1
FZD4
GABARAP
GABARAPL1
GMCL2
GOLGA2
GRAP2
GRB2
HIP1
IHO1
KLHL12
LMO3
LRRK2
MAGOHB
MAP1LC3A
MCRS1
NOL12
NUP62CL
OTULIN
PARD6A
PCBD1
PLA2G12A
POLI
PPM1A
PPP1R16B
PRKAA1
PRKCA
PRKCB
PRKCG
PRPF3
PRPF31
PSMF1
RAC1
RBFOX1
RBPMS
RHOA
RHOXF2
RNF185
RNPS1
RUNX2
RUSC1
SCNM1
SMURF1
SNF8
SNIP1
SORBS3
SSX2IP
TAB1
TDP2
THAP1
TIFA
TLE5
TP53
TPM3
TRAF2
U2AF2
UBAC1
UBE2D3
UIMC1
USP5
USP9X
VANGL1
VHL
WAS
WT1
YES1
ZBTB48
ZBTB8A
ZGPAT
ZNF165
ZNF250
ZNF263
ZNF410
ZNF581
Entrez ID
55110
1856
HPRD ID
08544
03690
Ensembl ID
ENSG00000111196
ENSG00000004975
Uniprot IDs
A0A023T6R1
F5H6P7
Q96A72
O14641
PDB IDs
5XJC
5YZG
6ICZ
6QDV
2REY
3CBX
3CBY
3CBZ
3CC0
4WIP
5LNP
5SUY
5SUZ
6IW3
6JCK
Enriched GO Terms of Interacting Partners
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