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CTSA and RHBDD1
Data Source:
BioGRID
(two hybrid)
CTSA
RHBDD1
Description
cathepsin A
rhomboid domain containing 1
Image
GO Annotations
Cellular Component
Extracellular Region
Lysosome
Endoplasmic Reticulum
Membrane
Azurophil Granule Lumen
Lysosomal Lumen
Intracellular Membrane-bounded Organelle
Extracellular Exosome
Lumenal Side Of Lysosomal Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Endoplasmic Reticulum Membrane
Mitochondrial Membrane
Endoplasmic Reticulum Quality Control Compartment
Molecular Function
Carboxypeptidase Activity
Serine-type Carboxypeptidase Activity
Enzyme Activator Activity
Serine-type Endopeptidase Activity
Protein Binding
Biological Process
Proteolysis
Glycosphingolipid Metabolic Process
Intracellular Protein Transport
Regulation Of Protein Stability
Neutrophil Degranulation
Regulation Of Catalytic Activity
Regulation Of Chaperone-mediated Autophagy
Negative Regulation Of Chaperone-mediated Autophagy
Apoptotic Process
Positive Regulation Of Protein Processing
Membrane Protein Intracellular Domain Proteolysis
Cellular Response To Unfolded Protein
Cellular Response To UV
ERAD Pathway
Negative Regulation Of Apoptotic Process
Post-translational Protein Modification
Spermatid Differentiation
Membrane Protein Proteolysis Involved In Retrograde Protein Transport, ER To Cytosol
Regulation Of Male Germ Cell Proliferation
Pathways
Glycosphingolipid metabolism
MHC class II antigen presentation
Sialic acid metabolism
Defective NEU1 causes sialidosis
Neutrophil degranulation
Drugs
Diseases
Galactosialidosis
GWAS
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Pulmonary function (
17903307
)
Interacting Genes
45 interacting genes:
AHNAK2
AQP2
AQP6
ARL13B
ASPH
BSND
CD79A
COQ9
CPLX4
CREB3L1
CSPG5
ERGIC3
FAM209A
FKBP7
FNDC9
GLB1
GORAB
HIBADH
LAMP2
LMNA
LTB4R2
MFSD14B
MGST3
MUC1
MYG1
NEU1
PSCA
REEP4
RHBDD1
RNF122
SAR1A
SGMS2
SIGLEC12
SLC18A1
SLC30A2
SPN
SSMEM1
STX2
THAP4
TMEM139
TMEM154
TMEM237
TMEM31
TMEM35A
TMX2
18 interacting genes:
CGRRF1
CMTM5
CREB3L1
CTSA
DAPK1
FBXO25
GYPC
LPCAT2
LRRK2
MFHAS1
NSDHL
PLEKHB2
RNF5
SEC22B
SLC66A2
TMEM42
TMEM86B
TMIE
Entrez ID
5476
84236
HPRD ID
02020
13206
Ensembl ID
ENSG00000064601
ENSG00000144468
Uniprot IDs
B4E324
P10619
X6R5C5
X6R8A1
Q8TEB9
PDB IDs
1IVY
3BP4
3BP7
3BXN
4AZ0
4AZ3
4CI9
4CIA
4CIB
4MWS
4MWT
6WIA
5EPP
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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