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CTSA

Description cathepsin A
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Lysosome
  • Endoplasmic Reticulum
  • Membrane
  • Azurophil Granule Lumen
  • Lysosomal Lumen
  • Intracellular Membrane-bounded Organelle
  • Extracellular Exosome
  • Lumenal Side Of Lysosomal Membrane
Molecular Function
  • Carboxypeptidase Activity
  • Serine-type Carboxypeptidase Activity
  • Enzyme Activator Activity
Biological Process
  • Proteolysis
  • Glycosphingolipid Metabolic Process
  • Intracellular Protein Transport
  • Regulation Of Protein Stability
  • Neutrophil Degranulation
  • Regulation Of Catalytic Activity
  • Regulation Of Chaperone-mediated Autophagy
  • Negative Regulation Of Chaperone-mediated Autophagy
Pathways
  • Glycosphingolipid metabolism
  • MHC class II antigen presentation
  • Sialic acid metabolism
  • Defective NEU1 causes sialidosis
  • Neutrophil degranulation
Drugs
Diseases
  • Galactosialidosis
GWAS
Interacting Genes 45 interacting genes: AHNAK2 AQP2 AQP6 ARL13B ASPH BSND CD79A COQ9 CPLX4 CREB3L1 CSPG5 ERGIC3 FAM209A FKBP7 FNDC9 GLB1 GORAB HIBADH LAMP2 LMNA LTB4R2 MFSD14B MGST3 MUC1 MYG1 NEU1 PSCA REEP4 RHBDD1 RNF122 SAR1A SGMS2 SIGLEC12 SLC18A1 SLC30A2 SPN SSMEM1 STX2 THAP4 TMEM139 TMEM154 TMEM237 TMEM31 TMEM35A TMX2
Entrez ID 5476
HPRD ID 02020
Ensembl ID ENSG00000064601
Uniprot IDs B4E324 P10619 X6R5C5 X6R8A1
PDB IDs 1IVY 3BP4 3BP7 3BXN 4AZ0 4AZ3 4CI9 4CIA 4CIB 4MWS 4MWT 6WIA
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025