XAF1 and TRIM50

		XAF1	TRIM50
Description		XIAP associated factor 1	tripartite motif containing 50
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Cytosol	Cytoplasm Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding	Protein Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Apoptotic Process Response To Interferon-beta Type I Interferon Signaling Pathway	Protein Ubiquitination
Pathways		Interferon alpha/beta signaling	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Immune reponse to smallpox (secreted IL-12p40) ( 22610502)
Interacting Genes		18 interacting genes: AKT1 APP BIRC7 CREBBP GLS2 LRSAM1 RFC5 RNF114 RNF166 SEPHS1 TP53 TRIM21 TRIM50 TRIM54 TRIML2 UBXN2B VCP XIAP	40 interacting genes: ARHGAP45 CDK18 CLK2 EFHC2 EPM2AIP1 FAM221B GCC1 HDAC6 IQUB KLHL2 L3MBTL2 LNX1 MEOX2 PIAS2 PLA2G6 RAD23A RSPH14 SNAI1 SPG21 SRC TEPSIN TRAF2 TRIM27 TSGA10IP TSSK3 UBASH3A UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2N UBTD1 USP2 XAF1 ZNF438 ZNF620
Entrez ID		54739	135892
HPRD ID		06978	15566
Ensembl ID		ENSG00000132530	ENSG00000146755
Uniprot IDs		Q6GPH4	B7ZLG2 Q2M204 Q86XT4
PDB IDs		2LXW
Enriched GO Terms of Interacting Partners?
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