TRIM50 and XAF1

		TRIM50	XAF1
Description		tripartite motif containing 50	XIAP associated factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleoplasm Mitochondrion Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity	Protein Binding Zinc Ion Binding
	Biological Process	Protein Ubiquitination	Apoptotic Process Response To Interferon-beta Type I Interferon Signaling Pathway
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Immune reponse to smallpox (secreted IL-12p40) ( 22610502)
Interacting Genes		40 interacting genes: ARHGAP45 CDK18 CLK2 EFHC2 EPM2AIP1 FAM221B GCC1 HDAC6 IQUB KLHL2 L3MBTL2 LNX1 MEOX2 PIAS2 PLA2G6 RAD23A RSPH14 SNAI1 SPG21 SRC TEPSIN TRAF2 TRIM27 TSGA10IP TSSK3 UBASH3A UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2N UBTD1 USP2 XAF1 ZNF438 ZNF620	18 interacting genes: AKT1 APP BIRC7 CREBBP GLS2 LRSAM1 RFC5 RNF114 RNF166 SEPHS1 TP53 TRIM21 TRIM50 TRIM54 TRIML2 UBXN2B VCP XIAP
Entrez ID		135892	54739
HPRD ID		15566	06978
Ensembl ID		ENSG00000146755	ENSG00000132530
Uniprot IDs		B7ZLG2 Q2M204 Q86XT4	Q6GPH4
PDB IDs			2LXW
Enriched GO Terms of Interacting Partners?
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