TRIM50 and FAM221B

		TRIM50	FAM221B
Description		tripartite motif containing 50	family with sequence similarity 221 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Protein Ubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Immune reponse to smallpox (secreted IL-12p40) ( 22610502)	Blood protein levels ( 28240269) Multiple sclerosis ( 31604244)
Interacting Genes		40 interacting genes: ARHGAP45 CDK18 CLK2 EFHC2 EPM2AIP1 FAM221B GCC1 HDAC6 IQUB KLHL2 L3MBTL2 LNX1 MEOX2 PIAS2 PLA2G6 RAD23A RSPH14 SNAI1 SPG21 SRC TEPSIN TRAF2 TRIM27 TSGA10IP TSSK3 UBASH3A UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2N UBTD1 USP2 XAF1 ZNF438 ZNF620	14 interacting genes: ANKRD11 CCDC13 CYSRT1 EFHC2 GSC2 KPRP KRT35 KRTAP10-8 KRTAP13-1 LBX1 LCE2C LZTS2 PLSCR2 TRIM50
Entrez ID		135892	392307
HPRD ID		15566	16675
Ensembl ID		ENSG00000146755	ENSG00000204930
Uniprot IDs		B7ZLG2 Q2M204 Q86XT4	A6H8Z2
PDB IDs
Enriched GO Terms of Interacting Partners?
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