PAF1 and MSL1

Data Source:
BioGRID (pull down)

		PAF1	MSL1
Description		PAF1 homolog, Paf1/RNA polymerase II complex component	MSL complex subunit 1
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Membrane Cdc73/Paf1 Complex Cell Junction Transcriptionally Active Chromatin	Nucleus Nucleoplasm Nuclear Speck MSL Complex
	Molecular Function	RNA Polymerase II Complex Binding Chromatin Binding Protein Binding	Chromatin Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Endodermal Cell Fate Commitment Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter MRNA Polyadenylation Histone Monoubiquitination Wnt Signaling Pathway Protein Ubiquitination Nucleosome Positioning Stem Cell Population Maintenance Positive Regulation Of Histone Methylation Positive Regulation Of MRNA 3'-end Processing Histone H2B Ubiquitination Protein Localization To Nucleus Negative Regulation Of Myeloid Cell Differentiation Cellular Response To Lipopolysaccharide Positive Regulation Of Cell Cycle G1/S Phase Transition	Histone H4-K16 Acetylation
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation E3 ubiquitin ligases ubiquitinate target proteins	HATs acetylate histones
Drugs
Diseases
GWAS			Asthma ( 31619474)
Interacting Genes		17 interacting genes: ENO1 ERCC6 FXR2 H1-2 H3C1 HSPB1 KAT8 KMT2A LEO1 MLLT1 MSL1 MSL2 MSL3 RNF20 SUMO2 TCEA1 TULP3	17 interacting genes: CRKL FCHSD2 H2BC21 HORMAD1 HSPB1 KPNB1 MORF4L1 MRGBP NUPR1 PAF1 PPM1G RAN RNF20 RNF40 SMARCC1 SNW1 UBE2D3
Entrez ID		54623	339287
HPRD ID		10140	19425
Ensembl ID		ENSG00000006712	ENSG00000188895
Uniprot IDs		A0A024R0H6 Q8N7H5	B3KWR7 Q68DK7
PDB IDs		4M6T 5ZYQ 6GMH 6TED	4B7Y 4B86 4DNC
Enriched GO Terms of Interacting Partners?
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