PAF1 and MSL3

Data Source:
BioGRID (pull down)

		PAF1	MSL3
Description		PAF1 homolog, Paf1/RNA polymerase II complex component	MSL complex subunit 3
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Membrane Cdc73/Paf1 Complex Cell Junction Transcriptionally Active Chromatin	Histone Acetyltransferase Complex Nucleus Nucleoplasm NuA4 Histone Acetyltransferase Complex MSL Complex
	Molecular Function	RNA Polymerase II Complex Binding Chromatin Binding Protein Binding	DNA Binding Protein Binding Methylated Histone Binding Histone Acetyltransferase Activity (H4-K16 Specific)
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Endodermal Cell Fate Commitment Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter MRNA Polyadenylation Histone Monoubiquitination Wnt Signaling Pathway Protein Ubiquitination Nucleosome Positioning Stem Cell Population Maintenance Positive Regulation Of Histone Methylation Positive Regulation Of MRNA 3'-end Processing Histone H2B Ubiquitination Protein Localization To Nucleus Negative Regulation Of Myeloid Cell Differentiation Cellular Response To Lipopolysaccharide Positive Regulation Of Cell Cycle G1/S Phase Transition	Chromatin Silencing Regulation Of Transcription, DNA-templated Histone Acetylation Histone Deacetylation Histone H4 Acetylation Histone H2A Acetylation Histone H4-K16 Acetylation
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation E3 ubiquitin ligases ubiquitinate target proteins	HATs acetylate histones
Drugs
Diseases
GWAS
Interacting Genes		17 interacting genes: ENO1 ERCC6 FXR2 H1-2 H3C1 HSPB1 KAT8 KMT2A LEO1 MLLT1 MSL1 MSL2 MSL3 RNF20 SUMO2 TCEA1 TULP3	8 interacting genes: APP CDK6 H3-4 H3C1 H4-16 H4C1 KAT8 PAF1
Entrez ID		54623	10943
HPRD ID		10140	05344
Ensembl ID		ENSG00000006712	ENSG00000005302
Uniprot IDs		A0A024R0H6 Q8N7H5	Q8N5Y2
PDB IDs		4M6T 5ZYQ 6GMH 6TED	2Y0N 3OA6 3OB9
Enriched GO Terms of Interacting Partners?
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