FXYD6 and SLC10A1

Data Source:
BioGRID (two hybrid)

		FXYD6	SLC10A1
Description		FXYD domain containing ion transport regulator 6	solute carrier family 10 member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane
	Molecular Function	Molecular_function Protein Binding Sodium Channel Regulator Activity Ion Channel Regulator Activity	Virus Receptor Activity Protein Binding Bile Acid:sodium Symporter Activity
	Biological Process	Biological_process Ion Transmembrane Transport Regulation Of Cardiac Conduction Regulation Of Sodium Ion Transmembrane Transporter Activity	Sodium Ion Transport Regulation Of Gene Expression Bile Acid And Bile Salt Transport Response To Nutrient Levels Cellular Response To Drug Bile Acid Signaling Pathway Response To Ethanol Viral Entry Into Host Cell Transmembrane Transport Regulation Of Bile Acid Secretion Response To 17alpha-ethynylestradiol
Pathways		Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS	Recycling of bile acids and salts
Drugs
Diseases
GWAS		Hippocampal volume in Alzheimer's disease dementia ( 29274321) Myopia ( 27182965)	Daytime sleep phenotypes ( 27126917) Metabolite levels ( 23823483) Triglyceride levels ( 30108155)
Interacting Genes		65 interacting genes: APCDD1L APH1A AQP6 ARL13B BCAR1 C4BPA CCDC90B CD74 CERS4 CLDN7 CLEC10A CREB3 CREB3L1 DERL2 EBP ELOVL2 ELOVL4 ERGIC3 FCER1G FFAR2 FPR2 GDF9 GJA8 GPR42 HAUS2 JAGN1 KCNJ6 LHFPL2 LHFPL5 LMNA MFF MGST3 MMGT1 OCIAD1 PEX12 PGRMC2 PPP1CC RBM48 RHBDL1 RHCG RNASEK SLC10A1 SLC10A6 SLC16A7 SLC30A2 SLC35C2 SLC35E1 SLC35E3 SLC39A2 SLC47A1 SVOP TLCD4 TLE1 TM4SF18 TMEM154 TMEM237 TMEM239 TMEM31 TMEM35A TMEM72 TMEM86B TMPPE TP53 TRIM27 UNC119	91 interacting genes: ABHD16A ACSL5 AGPAT3 ARL6IP6 ASGR1 ATP6V0B BMP10 C2 C8A CFHR5 CLDN19 CMTM3 COX20 CXCL9 CYB5R3 DERL1 DGAT2L6 FA2H FAM241B FAXDC2 FCER1G FDFT1 FXYD3 FXYD6 FXYD6-FXYD2 GAST GDE1 GIMAP5 GOSR2 GPR151 GPR152 IFITM2 IFITM3 IFTAP LRP10 LSS MAL MALL MFSD6 MS4A1 MYADML2 NEU1 NINJ2 ORMDL1 ORMDL2 ORMDL3 OTOP3 PEDS1-UBE2V1 PEX16 PKMYT1 RUSF1 SACM1L SCAMP4 SELENOK SFT2D1 SFT2D2 SFXN1 SLC12A7 SLC16A13 SLC25A46 SLC29A2 SLC35E4 SLC38A1 SLC38A7 SLC41A1 SLC66A2 SLC7A3 SMPD2 STX7 TAP1 TFRC TMBIM1 TMEM119 TMEM120B TMEM121 TMEM147 TMEM222 TMEM234 TMEM239 TMEM242 TMEM60 TMUB2 TOMM6 TRARG1 TSPO2 TVP23B UNC50 VAMP3 YIF1A YIPF4 YIPF6
Entrez ID		53826	6554
HPRD ID		09456	01672
Ensembl ID		ENSG00000137726	ENSG00000100652
Uniprot IDs		A0A024R3J8 Q9H0Q3	B2RA41 Q14973
PDB IDs
Enriched GO Terms of Interacting Partners?
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