FXYD6 and SLC39A2

Data Source:
BioGRID (two hybrid)

		FXYD6	SLC39A2
Description		FXYD domain containing ion transport regulator 6	solute carrier family 39 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Membrane Cytoplasmic Vesicle Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Molecular_function Protein Binding Sodium Channel Regulator Activity Ion Channel Regulator Activity	Zinc Ion Transmembrane Transporter Activity Protein Binding
	Biological Process	Biological_process Ion Transmembrane Transport Regulation Of Cardiac Conduction Regulation Of Sodium Ion Transmembrane Transporter Activity	Zinc Ion Transport Zinc Ion Transmembrane Transport
Pathways		Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS	Zinc influx into cells by the SLC39 gene family
Drugs
Diseases
GWAS		Hippocampal volume in Alzheimer's disease dementia ( 29274321) Myopia ( 27182965)
Interacting Genes		65 interacting genes: APCDD1L APH1A AQP6 ARL13B BCAR1 C4BPA CCDC90B CD74 CERS4 CLDN7 CLEC10A CREB3 CREB3L1 DERL2 EBP ELOVL2 ELOVL4 ERGIC3 FCER1G FFAR2 FPR2 GDF9 GJA8 GPR42 HAUS2 JAGN1 KCNJ6 LHFPL2 LHFPL5 LMNA MFF MGST3 MMGT1 OCIAD1 PEX12 PGRMC2 PPP1CC RBM48 RHBDL1 RHCG RNASEK SLC10A1 SLC10A6 SLC16A7 SLC30A2 SLC35C2 SLC35E1 SLC35E3 SLC39A2 SLC47A1 SVOP TLCD4 TLE1 TM4SF18 TMEM154 TMEM237 TMEM239 TMEM31 TMEM35A TMEM72 TMEM86B TMPPE TP53 TRIM27 UNC119	51 interacting genes: AQP1 AQP6 ARL13B BCL2L2 BTN2A2 C3orf52 C4orf3 CD79A CLCA4 CNR2 COL4A5 COMT CREB3L1 CXCR2 CYB561 EHHADH EMC6 FCER1G FXYD3 FXYD6 GJA8 GPR152 GPR42 KCNAB1 KCNAB2 LY6G6C MFSD6 MS4A13 PLN PNLIPRP1 SEC22A SLC18A1 SLC30A2 SLC30A8 SLC39A1 SLC39A9 SLC66A1 SLC7A1 SSMEM1 ST6GAL2 STATH TMEM107 TMEM14B TMEM229B TMEM237 TMEM54 TMEM60 TMEM86A TRHR UPK1B YIPF6
Entrez ID		53826	29986
HPRD ID		09456	15385
Ensembl ID		ENSG00000137726	ENSG00000165794
Uniprot IDs		A0A024R3J8 Q9H0Q3	Q9NP94
PDB IDs
Enriched GO Terms of Interacting Partners?
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