PMM1 and RAB6A

Data Source:
HPRD (two hybrid)

		PMM1	RAB6A
Description		phosphomannomutase 1	RAB6A, member RAS oncogene family
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GO Annotations	Cellular Component	Cytosol Neuronal Cell Body	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Membrane Secretory Granule Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Extracellular Exosome Endosome To Plasma Membrane Transport Vesicle
	Molecular Function	Phosphomannomutase Activity Protein Binding Metal Ion Binding	GTPase Activity Protein Binding GTP Binding Protein Domain Specific Binding Myosin V Binding
	Biological Process	Mannose Metabolic Process Protein N-linked Glycosylation GDP-mannose Biosynthetic Process Cellular Response To Leukemia Inhibitory Factor	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Viral Process Peptidyl-cysteine Methylation Antigen Processing And Presentation Protein Localization To Golgi Apparatus Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Neutrophil Degranulation Minus-end-directed Organelle Transport Along Microtubule
Pathways		Synthesis of GDP-mannose	Pre-NOTCH Processing in Golgi Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic Retrograde transport at the Trans-Golgi-Network TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Crohn's disease ( 26192919) Inflammatory bowel disease ( 26192919) Meat-related diet ( 32066663) Neuroticism ( 29255261) Refractive error ( 32231278)	Dimensional psychopathology (Cognitive) ( 29496196) Obesity-related traits ( 23251661)
Interacting Genes		5 interacting genes: CACNA1A MFHAS1 RAB6A RAB6B RCHY1	21 interacting genes: BICD1 BICD2 CHM CHML DCTN1 ERC1 FKBP2 GDI1 GOLGA1 GOLGA2 GOLGA4 GORAB KIF20A OCRL PMM1 RAB7A RABAC1 RABGAP1 RABGGTB SYTL5 TMF1
Entrez ID		5372	5870
HPRD ID		03473	01543
Ensembl ID		ENSG00000100417	ENSG00000175582
Uniprot IDs		A0A024R1U5 Q92871	A0A024R5H8 A0A024R5J5 P20340 Q53ET8
PDB IDs		2FUC 2FUE 6CFR 6CFS 6CFT 6CFU 6CFV	1YZQ 2GIL 3BBP 3CWZ 4DKX 5LEF
Enriched GO Terms of Interacting Partners?
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