RAB6A and TMF1

Data Source:
HPRD (in vitro)

		RAB6A	TMF1
Description		RAB6A, member RAS oncogene family	TATA element modulatory factor 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Membrane Secretory Granule Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Extracellular Exosome Endosome To Plasma Membrane Transport Vesicle	Golgi Membrane Nucleus Endoplasmic Reticulum Golgi Apparatus Cytosol
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Domain Specific Binding Myosin V Binding	DNA Binding Protein Binding Nuclear Receptor Coactivator Activity Androgen Receptor Binding
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Viral Process Peptidyl-cysteine Methylation Antigen Processing And Presentation Protein Localization To Golgi Apparatus Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Neutrophil Degranulation Minus-end-directed Organelle Transport Along Microtubule	Acrosome Assembly Positive Regulation Of Cytokine Production Spermatid Nucleus Differentiation Negative Regulation Of Gene Expression Flagellated Sperm Motility Androgen Receptor Signaling Pathway Luteinizing Hormone Secretion Leydig Cell Differentiation Defense Response To Bacterium Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Testosterone Secretion
Pathways		Pre-NOTCH Processing in Golgi Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic Retrograde transport at the Trans-Golgi-Network TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Dimensional psychopathology (Cognitive) ( 29496196) Obesity-related traits ( 23251661)	Meat-related diet ( 32066663) Metabolite levels ( 23823483)
Interacting Genes		21 interacting genes: BICD1 BICD2 CHM CHML DCTN1 ERC1 FKBP2 GDI1 GOLGA1 GOLGA2 GOLGA4 GORAB KIF20A OCRL PMM1 RAB7A RABAC1 RABGAP1 RABGGTB SYTL5 TMF1	9 interacting genes: AR CMTM5 FER GFI1B ITSN2 KAT2B NR3C1 RAB6A SMARCA4
Entrez ID		5870	7110
HPRD ID		01543	03081
Ensembl ID		ENSG00000175582	ENSG00000144747
Uniprot IDs		A0A024R5H8 A0A024R5J5 P20340 Q53ET8	A0A024R370 P82094 Q6PII6
PDB IDs		1YZQ 2GIL 3BBP 3CWZ 4DKX 5LEF
Enriched GO Terms of Interacting Partners?
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