RAB6A and KIF20A

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		RAB6A	KIF20A
Description		RAB6A, member RAS oncogene family	kinesin family member 20A
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Membrane Secretory Granule Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Extracellular Exosome Endosome To Plasma Membrane Transport Vesicle	Nucleus Nucleoplasm Golgi Apparatus Spindle Kinesin Complex Microtubule Midbody Cleavage Furrow Intercellular Bridge
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Domain Specific Binding Myosin V Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity Protein Kinase Binding
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Viral Process Peptidyl-cysteine Methylation Antigen Processing And Presentation Protein Localization To Golgi Apparatus Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Neutrophil Degranulation Minus-end-directed Organelle Transport Along Microtubule	Mitotic Cytokinesis Microtubule Bundle Formation Microtubule-based Movement Protein Transport Regulation Of Cytokinesis Midbody Abscission
Pathways		Pre-NOTCH Processing in Golgi Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic Retrograde transport at the Trans-Golgi-Network TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	MHC class II antigen presentation COPI-dependent Golgi-to-ER retrograde traffic Mitotic Telophase/Cytokinesis Kinesins
Drugs
Diseases
GWAS		Dimensional psychopathology (Cognitive) ( 29496196) Obesity-related traits ( 23251661)	Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		21 interacting genes: BICD1 BICD2 CHM CHML DCTN1 ERC1 FKBP2 GDI1 GOLGA1 GOLGA2 GOLGA4 GORAB KIF20A OCRL PMM1 RAB7A RABAC1 RABGAP1 RABGGTB SYTL5 TMF1	6 interacting genes: CDC14A FAM214B LRRK1 RAB6A RAB6B ZRANB2
Entrez ID		5870	10112
HPRD ID		01543	09292
Ensembl ID		ENSG00000175582	ENSG00000112984
Uniprot IDs		A0A024R5H8 A0A024R5J5 P20340 Q53ET8	O95235
PDB IDs		1YZQ 2GIL 3BBP 3CWZ 4DKX 5LEF	6YIP
Enriched GO Terms of Interacting Partners?
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