CD244 and PCGF1

Data Source:
BioGRID (proximity labelling technology)

		CD244	PCGF1
Description		CD244 molecule	polycomb group ring finger 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane	Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex
	Molecular Function	Protein Binding Signaling Receptor Activity MHC Class I Protein Binding	Protein Binding Protein C-terminus Binding Metal Ion Binding Promoter-specific Chromatin Binding
	Biological Process	Adaptive Immune Response Natural Killer Cell Activation Involved In Immune Response Signal Transduction Positive Regulation Of Interferon-gamma Production Positive Regulation Of Interleukin-8 Production Innate Immune Response Leukocyte Migration Positive Regulation Of Inositol Phosphate Biosynthetic Process Positive Regulation Of Granzyme B Production	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Silencing Regulation Of Transcription, DNA-templated Histone H2A Monoubiquitination Histone H2A-K119 Monoubiquitination
Pathways		Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494) White blood cell count ( 32888494)
Interacting Genes		5 interacting genes: ARHGEF7 CD247 CD48 LAT SH2D1B	12 interacting genes: BCOR CALCOCO2 CBX6 CBX7 FCHO1 MUC7 PCGF5 RNF125 RNF2 TRIM55 UBE2D3 UBE2U
Entrez ID		51744	84759
HPRD ID		16121	11404
Ensembl ID		ENSG00000122223	ENSG00000115289
Uniprot IDs		Q9BZW8	Q9BSM1
PDB IDs			4HPL 4HPM 5JH5
Enriched GO Terms of Interacting Partners?
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