PCGF1 and BCOR

Data Source:
BioGRID (two hybrid)

		PCGF1	BCOR
Description		polycomb group ring finger 1	BCL6 corepressor
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GO Annotations	Cellular Component	Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex	Nucleus Nucleoplasm BCOR Complex
	Molecular Function	Protein Binding Protein C-terminus Binding Metal Ion Binding Promoter-specific Chromatin Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Corepressor Activity Ubiquitin-protein Transferase Activity Protein Binding Transcription Factor Binding Heat Shock Protein Binding Histone Deacetylase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Silencing Regulation Of Transcription, DNA-templated Histone H2A Monoubiquitination Histone H2A-K119 Monoubiquitination	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Histone H3-K36 Methylation Blastocyst Hatching Heart Development Negative Regulation Of Bone Mineralization Histone H2A Monoubiquitination Odontogenesis Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Histone H3-K4 Methylation Roof Of Mouth Development Specification Of Axis Polarity Negative Regulation Of Tooth Mineralization
Pathways
Drugs
Diseases			Anophthalmia and microphthalmia (A/M)
GWAS			Pit-and-Fissure caries ( 23470693) Platelet count ( 29403010) Refractive error ( 32231278) Venous thromboembolism ( 31676865)
Interacting Genes		12 interacting genes: BCOR CALCOCO2 CBX6 CBX7 FCHO1 MUC7 PCGF5 RNF125 RNF2 TRIM55 UBE2D3 UBE2U	17 interacting genes: BCL6 CPNE1 CPNE2 CPNE4 HDAC1 HDAC3 HDAC4 HDAC5 HDAC6 MLLT3 NAA10 NACC1 PCGF1 PCGF3 SP1 UBTD1 USP7
Entrez ID		84759	54880
HPRD ID		11404	06458
Ensembl ID		ENSG00000115289	ENSG00000183337
Uniprot IDs		Q9BSM1	Q6W2J9
PDB IDs		4HPL 4HPM 5JH5	2N1L 3BIM 4HPL 6B7G
Enriched GO Terms of Interacting Partners?
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