ECSIT and BFSP2

Data Source:
BioGRID (two hybrid)

		ECSIT	BFSP2
Description		ECSIT signaling integrator	beaded filament structural protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Inner Membrane Cytosol	Intermediate Filament Plasma Membrane Cell Cortex
	Molecular Function	Protein Binding	Structural Constituent Of Cytoskeleton Structural Constituent Of Eye Lens Protein Binding
	Biological Process	Mitochondrial Respiratory Chain Complex I Assembly Innate Immune Response Regulation Of Oxidoreductase Activity Regulation Of Protein Complex Stability	Visual Perception Intermediate Filament Organization Cell Maturation Response To Stimulus Lens Fiber Cell Development
Pathways		MyD88:MAL(TIRAP) cascade initiated on plasma membrane Complex I biogenesis TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation MyD88 cascade initiated on plasma membrane
Drugs
Diseases
GWAS		Presence of antiphospholipid antibodies ( 27098658)
Interacting Genes		52 interacting genes: A2M AP1M2 APOE APP BFSP2 BLMH C1orf109 CDC37 CEP55 CTNNA3 CYP2C18 CYP2C8 CYP2C9 DNAJB1 DTX2 ELAVL3 EXOC6 EXOSC1 FARSA FBXL12 FBXW4 GCDH GEM IFIT3 IFIT5 IMMT LONP1 LOXL4 MAGEB2 MAST1 MKRN3 NFKB1 NXF1 PAXIP1 PI4K2A PRDX2 PSEN1 RAB3A RAD23A RELA RHEB RNF32 SETDB1 SMAD1 SMAD4 SMURF1 STAMBPL1 STRN4 TARS3 TRAF6 TRIM59 TSSK3	56 interacting genes: ABI3 AMOTL2 ANKRD33 ATF4 BEX3 BEX5 BFSP1 BICRAL BLOC1S2 C3orf62 CAGE1 CALCOCO1 CCDC153 CCDC183 CDCA4 CDR2L CEP44 CEP63 COPS6 CT55 DISC1 DMAP1 ECSIT HAUS1 HGS KRT14 KRT24 KRT27 KRT31 KRT37 MAGEA6 MBIP MCCD1 MYOG OIP5 PBX2 PBX4 POU6F2 PPP1R13B PSMC5 RINT1 RNASE10 SAPCD2 SCOC SERTAD3 SNAPC5 SNAPIN SUFU SYCE1 SYCE1L TRIB3 USHBP1 USP54 WASHC3 ZNF343 ZNF620
Entrez ID		51295	8419
HPRD ID		12225	04444
Ensembl ID		ENSG00000130159	ENSG00000170819
Uniprot IDs		Q9BQ95	Q13515
PDB IDs
Enriched GO Terms of Interacting Partners?
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