SLC35C2 and SLC12A5

Data Source:
BioGRID (affinity chromatography technology)

		SLC35C2	SLC12A5
Description		solute carrier family 35 member C2	solute carrier family 12 member 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Integral Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Neuron Projection Neuronal Cell Body Synapse Cell Periphery
	Molecular Function	Antiporter Activity	Chloride Transmembrane Transporter Activity Potassium:chloride Symporter Activity
	Biological Process	Negative Regulation Of Gene Expression UDP-glucose Transmembrane Transport Protein O-linked Fucosylation Positive Regulation Of Notch Signaling Pathway	Ion Transport Cellular Ion Homeostasis Cell Volume Homeostasis Hypotonic Response Chemical Synaptic Transmission Learning Cellular Chloride Ion Homeostasis Multicellular Organism Growth Thermosensory Behavior Response To Drug Chloride Ion Homeostasis Potassium Ion Homeostasis Dendritic Spine Development Chloride Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways			Cation-coupled Chloride cotransporters
Drugs			Potassium chloride Bumetanide
Diseases
GWAS			Chronotype ( 30696823) Crohn's disease ( 28067908) General risk tolerance (MTAG) ( 30643258) Inflammatory bowel disease ( 28067908) Reticulocyte count ( 32888494) Systemic sclerosis ( 29293537) Triglyceride levels ( 32154731)
Interacting Genes		91 interacting genes: ACSL5 ADIPOQ AGPAT3 AGPAT4 APOD ARL6IP1 ASGR1 ATP13A1 BCL2L2 BMP10 C14orf180 C2 C4orf3 CCDC167 CLDN19 CMTM5 CNIH1 COL4A5 CREB3 CREB3L1 CYB561 CYBC1 DNAJC30 EFNA5 EMP3 FAM3C FDFT1 FFAR2 FXYD3 FXYD6 FXYD6-FXYD2 GIMAP5 GOLT1A GPR152 ITGAM LAT LEPROTL1 LHFPL5 LPAR3 MAL MAL2 MALL MS4A1 NRM ORMDL1 ORMDL3 PDCD1LG2 PEX16 PLN PLP2 PNLIPRP1 PRB1 RUSF1 SACM1L SEC22A SEC22B SELENOK SERP1 SLC10A6 SLC12A7 SLC30A3 SLC35F1 SLC66A1 SMCO4 SSMEM1 STRIT1 STX3 SYNDIG1 SYS1 TAP1 THBD TMEM107 TMEM14B TMEM239 TMEM31 TMEM50B TMEM65 TMEM86A TPRG1 TSNARE1 TSPAN2 TSPAN33 TVP23B UNC93B1 UPK1B VAPB VEGFA VTI1B YIF1A YIPF4 YIPF6	2 interacting genes: CCR4 F2RL1
Entrez ID		51006	57468
HPRD ID		15371	09469
Ensembl ID		ENSG00000080189	ENSG00000124140
Uniprot IDs		B7Z6R4 Q9NQQ7	Q9H2X9
PDB IDs			6M23
Enriched GO Terms of Interacting Partners?
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