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SLC35C2 and LAT
Data Source:
BioGRID
(two hybrid)
SLC35C2
LAT
Description
solute carrier family 35 member C2
linker for activation of T cells
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Endoplasmic Reticulum-Golgi Intermediate Compartment
Golgi Apparatus
Cis-Golgi Network
Integral Component Of Membrane
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Immunological Synapse
Golgi Apparatus
Plasma Membrane
COP9 Signalosome
Integral Component Of Membrane
Membrane Raft
Molecular Function
Antiporter Activity
Protein Binding
Protein Kinase Binding
Signaling Receptor Complex Adaptor Activity
Biological Process
Negative Regulation Of Gene Expression
UDP-glucose Transmembrane Transport
Protein O-linked Fucosylation
Positive Regulation Of Notch Signaling Pathway
MAPK Cascade
Adaptive Immune Response
Inflammatory Response
Immune Response
Integrin-mediated Signaling Pathway
Ras Protein Signal Transduction
Calcium-mediated Signaling
Intracellular Signal Transduction
Fc-epsilon Receptor Signaling Pathway
T Cell Activation
Mast Cell Degranulation
Positive Regulation Of Protein Kinase Activity
T Cell Receptor Signaling Pathway
Regulation Of T Cell Activation
Pathways
GPVI-mediated activation cascade
Generation of second messenger molecules
Drugs
Diseases
GWAS
Allergic disease (asthma, hay fever or eczema) (
29679657
)
Crohn's disease (
21102463
)
Educational attainment (
25201988
)
Interacting Genes
91 interacting genes:
ACSL5
ADIPOQ
AGPAT3
AGPAT4
APOD
ARL6IP1
ASGR1
ATP13A1
BCL2L2
BMP10
C14orf180
C2
C4orf3
CCDC167
CLDN19
CMTM5
CNIH1
COL4A5
CREB3
CREB3L1
CYB561
CYBC1
DNAJC30
EFNA5
EMP3
FAM3C
FDFT1
FFAR2
FXYD3
FXYD6
FXYD6-FXYD2
GIMAP5
GOLT1A
GPR152
ITGAM
LAT
LEPROTL1
LHFPL5
LPAR3
MAL
MAL2
MALL
MS4A1
NRM
ORMDL1
ORMDL3
PDCD1LG2
PEX16
PLN
PLP2
PNLIPRP1
PRB1
RUSF1
SACM1L
SEC22A
SEC22B
SELENOK
SERP1
SLC10A6
SLC12A7
SLC30A3
SLC35F1
SLC66A1
SMCO4
SSMEM1
STRIT1
STX3
SYNDIG1
SYS1
TAP1
THBD
TMEM107
TMEM14B
TMEM239
TMEM31
TMEM50B
TMEM65
TMEM86A
TPRG1
TSNARE1
TSPAN2
TSPAN33
TVP23B
UNC93B1
UPK1B
VAPB
VEGFA
VTI1B
YIF1A
YIPF4
YIPF6
95 interacting genes:
APH1A
ASGR2
BCL2L13
BSCL2
CAMLG
CBL
CD244
CD3G
CD4
CD53
CD8A
CDIP1
CLDN2
CLDN5
CLDN7
CREB3
CXorf66
CYBC1
EGFR
FCGR1A
FCGR2A
FFAR2
FFAR3
FKBP7
FYN
GAB2
GJA8
GJB1
GJB3
GOLM1
GPR101
GPR151
GPR152
GPR42
GRAP
GRAP2
GRB2
ITK
JSRP1
KASH5
KCTD17
KIR2DL3
LCK
LCP2
LEUTX
LHFPL1
LHFPL5
LMNA
MAP1LC3C
MAP4K1
MEOX2
MFF
MFSD14B
MFSD5
MRPS18B
MS4A7
MTIF3
NDUFAF2
OPRM1
PIK3R1
PLCG1
PLCG2
PRR4
PSCA
PTPN1
PTPN6
PTPRJ
SAR1A
SERINC2
SGTA
SGTB
SH3BP2
SHB
SLA
SLC14A2
SLC16A2
SLC18A1
SLC19A3
SLC26A6
SLC35C2
SLC51B
SLPI
SSMEM1
SYK
SYT2
THAP4
TM4SF18
TMEM237
TMEM45B
TMEM80
TNFRSF10D
VAV1
ZAP70
ZDHHC7
ZHX2
Entrez ID
51006
27040
HPRD ID
15371
03832
Ensembl ID
ENSG00000080189
ENSG00000213658
Uniprot IDs
B7Z6R4
Q9NQQ7
A0A024QZD6
O43561
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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