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SLC35C2 and ITGAM
Data Source:
BioGRID
(two hybrid)
SLC35C2
ITGAM
Description
solute carrier family 35 member C2
integrin subunit alpha M
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Endoplasmic Reticulum-Golgi Intermediate Compartment
Golgi Apparatus
Cis-Golgi Network
Integral Component Of Membrane
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Extracellular Space
Plasma Membrane
Integrin Complex
External Side Of Plasma Membrane
Cell Surface
Integrin AlphaM-beta2 Complex
Specific Granule Membrane
Plasma Membrane Raft
Extracellular Exosome
Tertiary Granule Membrane
Molecular Function
Antiporter Activity
Amyloid-beta Binding
Complement Component C3b Binding
Integrin Binding
Protein Binding
Heat Shock Protein Binding
Cargo Receptor Activity
Metal Ion Binding
Biological Process
Negative Regulation Of Gene Expression
UDP-glucose Transmembrane Transport
Protein O-linked Fucosylation
Positive Regulation Of Notch Signaling Pathway
Microglial Cell Activation
Receptor-mediated Endocytosis
Phagocytosis, Engulfment
Cell Adhesion
Integrin-mediated Signaling Pathway
Ectodermal Cell Differentiation
Cytokine-mediated Signaling Pathway
Extracellular Matrix Organization
Forebrain Development
Positive Regulation Of Superoxide Anion Generation
Toll-like Receptor 4 Signaling Pathway
Neutrophil Degranulation
Positive Regulation Of Neutrophil Degranulation
Innate Immune Response
Negative Regulation Of Dopamine Metabolic Process
Leukocyte Migration
Positive Regulation Of Protein Targeting To Membrane
Apoptotic Signaling Pathway
Amyloid-beta Clearance
Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules
Positive Regulation Of Hippocampal Neuron Apoptotic Process
Complement-mediated Synapse Pruning
Vertebrate Eye-specific Patterning
Positive Regulation Of Neuron Death
Positive Regulation Of Microglial Cell Mediated Cytotoxicity
Cell Surface Receptor Signaling Pathway Involved In Cell-cell Signaling
Positive Regulation Of Prostaglandin-E Synthase Activity
Pathways
Toll Like Receptor 4 (TLR4) Cascade
Cell surface interactions at the vascular wall
Integrin cell surface interactions
Interleukin-4 and Interleukin-13 signaling
Neutrophil degranulation
Drugs
Diseases
GWAS
Apolipoprotein A1 levels (
32203549
)
Autoimmune thyroid diseases (Graves disease or Hashimoto's thyroiditis) (
22922229
)
Graves' disease (
22922229
)
IgA nephropathy (
25305756
)
Serum metabolite levels (CMS) (
31636271
)
Systemic lupus erythematosus (
27399966
18204446
24871463
26606652
23273568
26502338
18204098
21408207
19165918
28714469
19838195
)
Systemic lupus erythematosus and Systemic sclerosis (
23740937
)
Interacting Genes
91 interacting genes:
ACSL5
ADIPOQ
AGPAT3
AGPAT4
APOD
ARL6IP1
ASGR1
ATP13A1
BCL2L2
BMP10
C14orf180
C2
C4orf3
CCDC167
CLDN19
CMTM5
CNIH1
COL4A5
CREB3
CREB3L1
CYB561
CYBC1
DNAJC30
EFNA5
EMP3
FAM3C
FDFT1
FFAR2
FXYD3
FXYD6
FXYD6-FXYD2
GIMAP5
GOLT1A
GPR152
ITGAM
LAT
LEPROTL1
LHFPL5
LPAR3
MAL
MAL2
MALL
MS4A1
NRM
ORMDL1
ORMDL3
PDCD1LG2
PEX16
PLN
PLP2
PNLIPRP1
PRB1
RUSF1
SACM1L
SEC22A
SEC22B
SELENOK
SERP1
SLC10A6
SLC12A7
SLC30A3
SLC35F1
SLC66A1
SMCO4
SSMEM1
STRIT1
STX3
SYNDIG1
SYS1
TAP1
THBD
TMEM107
TMEM14B
TMEM239
TMEM31
TMEM50B
TMEM65
TMEM86A
TPRG1
TSNARE1
TSPAN2
TSPAN33
TVP23B
UNC93B1
UPK1B
VAPB
VEGFA
VTI1B
YIF1A
YIPF4
YIPF6
55 interacting genes:
ABHD16A
AQP6
ARL13B
AUP1
C3
CD209
CD79A
CERS4
CFH
CLEC4M
CLRN1
CREB3L1
DKK4
ELANE
ELOVL4
ERGIC3
FGG
GJA8
GJB1
GORAB
GP1BA
GPR42
HP
HSD17B13
ICAM1
ICAM2
ICAM4
IRAK1
ITGB2
JAM3
KASH5
KCNJ6
KIR2DL3
LMNA
MGST3
MMGT1
MRM1
MUC1
PGRMC2
PIGP
PLAUR
REEP2
REEP4
RUSF1
SCN3B
SHARPIN
SLC10A6
SLC35C2
SYT2
THY1
TMEM14B
TMEM229B
TMEM31
TMEM52B
TMX2
Entrez ID
51006
3684
HPRD ID
15371
00411
Ensembl ID
ENSG00000080189
ENSG00000169896
Uniprot IDs
B7Z6R4
Q9NQQ7
P11215
PDB IDs
1A8X
1BHO
1BHQ
1IDN
1IDO
1JLM
1M1U
1MF7
1N9Z
1NA5
2LKE
2LKJ
3Q3G
3QA3
4M76
4XW2
6RHW
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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