STMN3 and TRIM69

Data Source:
BioGRID (two hybrid)

		STMN3	TRIM69
Description		stathmin 3	tripartite motif containing 69
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Growth Cone Neuron Projection	Nucleus Cytoplasm Cytosol Nuclear Speck
	Molecular Function	Protein Binding Tubulin Binding Protein Domain Specific Binding	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Microtubule Depolymerization Nervous System Development Regulation Of Microtubule Polymerization Or Depolymerization Cytoplasmic Microtubule Organization Neuron Projection Development Negative Regulation Of Rac Protein Signal Transduction Regulation Of GTPase Activity Regulation Of Cytoskeleton Organization	Protein Polyubiquitination Apoptotic Process Protein Ubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma or allergic disease (pleiotropy) ( 29785011) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Leukocyte telomere length ( 32109421) Mean corpuscular hemoglobin ( 32888494) Prostate cancer ( 23535732) Refractive error ( 32231278) Ulcerative colitis ( 28067908 21297633)	Estimated glomerular filtration rate in non-diabetics ( 31451708)
Interacting Genes		27 interacting genes: ANKRD11 C1orf109 CARD9 CLIC3 EXOC8 GLP1R GPANK1 HGS KAT5 KIFC3 KRT34 LTB4R2 MIPOL1 MKRN3 MNS1 NKX3-1 P4HA3 PLEKHA7 POLR1C SMARCD1 SPCS2 TBC1D21 TRIM69 TRPC5 TXLNB UBQLN1 ZNF76	53 interacting genes: AIFM2 APP ASNS ATP5MC1 BEX2 BIN3 C4orf45 CDSN DVL1 ETFDH FAM110A FAM161A FAM90A1 FKBP1B GEM HAUS1 HGS IYD KLHL38 KRT17 LARP1B LYSMD1 MAGEA4 MAJIN MED20 MID2 NEK8 NTAQ1 PML POLR3K PPP1R18 RECK RINT1 RSPH14 SF1 SF3A3 SKIL STMN3 SYCE2 SYNE4 TNNT2 TRIM44 TRIM54 TRIM55 TRIM63 UBE2D1 UBE2D3 UBE2E1 UBE2H UBE2N WASHC1 WWOX ZNF483
Entrez ID		50861	140691
HPRD ID		16324	11518
Ensembl ID		ENSG00000197457	ENSG00000185880
Uniprot IDs		Q9NZ72	H0YL66 Q86WT6
PDB IDs			4NQJ 6YXE
Enriched GO Terms of Interacting Partners?
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