MYH2 and DGKD

Data Source:
HPRD (in vitro)

		MYH2	DGKD
Description		myosin heavy chain 2	diacylglycerol kinase delta
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Muscle Myosin Complex Cell-cell Junction Myofibril Sarcomere Myosin Filament Protein-containing Complex	Nucleus Cytoplasm Cytosol Plasma Membrane Clathrin-coated Pit
	Molecular Function	Microfilament Motor Activity Protein Binding Calmodulin Binding ATP Binding Actin Filament Binding	NAD+ Kinase Activity Diacylglycerol Kinase Activity Protein Binding ATP Binding Kinase Binding Diacylglycerol Binding Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Muscle Contraction Muscle Filament Sliding Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis	Phosphatidic Acid Biosynthetic Process Endocytosis Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Multicellular Organism Development Response To Organic Substance Protein Transport Second-messenger-mediated Signaling Platelet Activation Intracellular Signal Transduction Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Diacylglycerol Metabolic Process Lipid Phosphorylation Negative Regulation Of Protein Kinase C Signaling Positive Regulation Of Clathrin-dependent Endocytosis
Pathways		Regulation of actin dynamics for phagocytic cup formation FCGR3A-mediated phagocytosis	Effects of PIP2 hydrolysis
Drugs			Phosphatidyl serine alpha-Tocopherol succinate
Diseases
GWAS			Bilirubin levels ( 20639394 32084209) Calcium levels ( 24068962 29403010 20705733) Crohn's disease ( 22412388) Glaucoma (primary open-angle) ( 29891935) Kidney stones ( 31729369) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494 27863252) Total body bone mineral density ( 29304378) Type 2 diabetes ( 32499647 30718926) Urinary calcium excretion ( 31993563)
Interacting Genes		7 interacting genes: AMPD1 DGKD DUX4L9 OBSCN PRKCE PTK2B S100A4	8 interacting genes: DGKH DYSF HAX1 IGSF21 MYH2 PRKCA SREK1 TNFRSF14
Entrez ID		4620	8527
HPRD ID		01173	03492
Ensembl ID		ENSG00000125414	ENSG00000077044
Uniprot IDs		Q9UKX2	A0A024R495 Q16760
PDB IDs			1R79 3BQ7
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?