SGCB and SGCG

Data Source:
HPRD (in vitro)

		SGCB	SGCG
Description		sarcoglycan beta	sarcoglycan gamma
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Integral Component Of Plasma Membrane Dystrophin-associated Glycoprotein Complex Sarcoglycan Complex Sarcolemma	Cytoplasm Cytoskeleton Plasma Membrane Sarcoglycan Complex Integral Component Of Membrane Sarcolemma
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Muscle Organ Development Muscle Fiber Development Cardiac Muscle Cell Development Vascular Associated Smooth Muscle Cell Development	Muscle Organ Development Cardiac Muscle Tissue Development Heart Contraction
Pathways
Drugs
Diseases		Sarcoglycanopathies, including: Limb-girdle muscular dystrophy (LGMD) 2C; Limb-girdle muscular dystrophy (LGMD) 2D; Limb-girdle muscular dystrophy (LGMD) 2E; Limb-girdle muscular dystrophy (LGMD) 2F Limb-girdle muscular dystrophy (LGMD)	Sarcoglycanopathies, including: Limb-girdle muscular dystrophy (LGMD) 2C; Limb-girdle muscular dystrophy (LGMD) 2D; Limb-girdle muscular dystrophy (LGMD) 2E; Limb-girdle muscular dystrophy (LGMD) 2F Limb-girdle muscular dystrophy (LGMD)
GWAS			Alanine aminotransferase levels ( 31219225) Asthma ( 27611488) Atrial fibrillation ( 30061737) Bipolar disorder ( 21738484) Central corneal thickness ( 29760442) Corneal structure ( 23291589) Number of alcoholic drinks required to feel an effect (first five times drinking) ( 31270906) Type 2 diabetes ( 23300278)
Interacting Genes		22 interacting genes: ADAM33 ADRA1A APOL3 BRICD5 CLEC7A CMTM5 EHHADH HTR2C LTB4R2 MAL MGST2 NINJ1 PTTG1IP SGCA SGCD SGCG SGCZ SLC52A1 SMIM3 TMEM11 TNF TRIM63	20 interacting genes: APP CCT6A CLDN5 DNAJB6 DYSF ENO1 ENO3 FLNC HSPA1B MYBPC1 MYBPC2 MYLPF PSAP PYGM SGCB SGCD SPACA1 SSPN SUCLG2 TTN
Entrez ID		6443	6445
HPRD ID		02942	07039
Ensembl ID		ENSG00000163069	ENSG00000102683
Uniprot IDs		Q16585 Q5U0N0	Q13326
PDB IDs
Enriched GO Terms of Interacting Partners?
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