MAGEA6 and TRIM26

Data Source:
BioGRID (two hybrid, two hybrid)

		MAGEA6	TRIM26
Description		MAGE family member A6	tripartite motif containing 26
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component	Cellular_component Nucleus Cytoplasm Cytosol
	Molecular Function	Molecular_function Protein Binding	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Biological_process	Regulation Of Gene Expression Protein Ubiquitination Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Negative Regulation Of Viral Release From Host Cell
Pathways			Interferon gamma signaling
Drugs
Diseases
GWAS			Anger ( 24489884) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) General cognitive ability ( 29844566) Hematocrit ( 32888494) LDL cholesterol levels ( 32203549) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Medication use (anti-inflammatory and antirheumatic products, non-steroids) ( 31015401) Neuroticism ( 29255261) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Schizophrenia ( 21926974 22883433 30285260) Squamous cell lung carcinoma ( 28604730) Triglyceride levels ( 32203549)
Interacting Genes		74 interacting genes: ACOT7 ACTN3 AKAP9 ANKRD26P1 APOA4 ARFIP1 ATP6V1G1 ATPAF2 BCL7B BET1 BFSP2 BOLA3 C1orf216 CAMTA2 CBFA2T2 CCDC146 CCDC185 CCDC187 CCDC24 COL4A6 CTF1 DLGAP3 DLGAP4 DNTTIP1 ELMOD3 EXOC5 FAM214A FRMPD1 GADD45GIP1 GCSH GFOD1 HAUS1 HLA-DRB4 HNRNPM IQUB KIF27 KLHL38 LCORL LIN37 LIN52 LSM2 MCM7 MCRS1 MED21 MID2 MIPOL1 MORN3 MSGN1 NCK2 NOSTRIN PCBD2 PDE4D RASSF10 RASSF4 RCOR3 REX1BD RPL37A RUSC1 S100A14 S100A9 SH2D4A SMARCD1 SNAP47 SNX4 SON STAMBPL1 STX5 TRIM26 TRIM28 TSPYL6 TULP3 TXNDC9 XRCC4 ZNF76	27 interacting genes: BEND7 BIVM EPN2 EPN3 INCA1 IRF3 LMNA MACROH2A1 MAGEA6 MIR138-2 MIR18B MNAT1 OTUB2 PHF7 RABEP1 RNF10 RNF126 SUMO2 THAP1 TLE5 TRIM41 UBE2D1 UBE2D2 UBE2D3 USP36 USP39 USP5
Entrez ID		4105	7726
HPRD ID		02168	02901
Ensembl ID		ENSG00000197172	ENSG00000234127
Uniprot IDs		P43360	A0A024RCP3 Q12899
PDB IDs
Enriched GO Terms of Interacting Partners?
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