MAGEA6 and LCORL

Data Source:
BioGRID (two hybrid)

		MAGEA6	LCORL
Description		MAGE family member A6	ligand dependent nuclear receptor corepressor like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component	Nucleus
	Molecular Function	Molecular_function Protein Binding	DNA Binding Protein Binding Histone Methyltransferase Binding
	Biological Process	Biological_process	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS			Adult body size ( 32376654) Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU) ( 24025145) Alzheimer's disease progression score ( 29860282) Birth length ( 25281659) Birth weight ( 23202124 31043758 27680694) BMI at 1 year old ( 31575865) BMI at 1.5 years old ( 31575865) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Chronotype ( 30696823) Colorectal cancer (diet interaction) ( 24743840) Diverticular disease ( 30177863) Familial squamous cell lung carcinoma ( 29924316) General risk tolerance (MTAG) ( 30643258) Hand grip strength ( 29691431) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 30598549) Height ( 21998595 28552196 20881960 22021425 25282103 25429064 19343178 23563607 31562340 28270201 18391951 18391952 20189936) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 25673412) Infant length ( 25281659) Offspring birth weight ( 31043758) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Reticulocyte fraction of red cells ( 32888494) Systolic blood pressure ( 30224653 30578418) Triglyceride levels ( 32203549) Type 2 diabetes ( 30297969) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for BMI in smokers ( 28443625) Waist circumference adjusted for body mass index ( 28552196 25673412) Weight ( 28552196) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		74 interacting genes: ACOT7 ACTN3 AKAP9 ANKRD26P1 APOA4 ARFIP1 ATP6V1G1 ATPAF2 BCL7B BET1 BFSP2 BOLA3 C1orf216 CAMTA2 CBFA2T2 CCDC146 CCDC185 CCDC187 CCDC24 COL4A6 CTF1 DLGAP3 DLGAP4 DNTTIP1 ELMOD3 EXOC5 FAM214A FRMPD1 GADD45GIP1 GCSH GFOD1 HAUS1 HLA-DRB4 HNRNPM IQUB KIF27 KLHL38 LCORL LIN37 LIN52 LSM2 MCM7 MCRS1 MED21 MID2 MIPOL1 MORN3 MSGN1 NCK2 NOSTRIN PCBD2 PDE4D RASSF10 RASSF4 RCOR3 REX1BD RPL37A RUSC1 S100A14 S100A9 SH2D4A SMARCD1 SNAP47 SNX4 SON STAMBPL1 STX5 TRIM26 TRIM28 TSPYL6 TULP3 TXNDC9 XRCC4 ZNF76	4 interacting genes: CTBP1 CTBP2 MAGEA6 MIR206
Entrez ID		4105	254251
HPRD ID		02168	10088
Ensembl ID		ENSG00000197172	ENSG00000178177
Uniprot IDs		P43360	A0A1B0GVP4 B4DSW0 Q8N3X6
PDB IDs
Enriched GO Terms of Interacting Partners?
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