TRIM26 and EPN3

Data Source:
BioGRID (two hybrid)

		TRIM26	EPN3
Description		tripartite motif containing 26	epsin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleus Cytoplasm Cytosol	Nucleus Nucleoplasm Endosome Plasma Membrane Clathrin-coated Pit Extrinsic Component Of Plasma Membrane Clathrin Vesicle Coat Clathrin-coated Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Phospholipid Binding Clathrin Binding EH Domain Binding
	Biological Process	Regulation Of Gene Expression Protein Ubiquitination Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Negative Regulation Of Viral Release From Host Cell	Endocytosis
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Anger ( 24489884) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) General cognitive ability ( 29844566) Hematocrit ( 32888494) LDL cholesterol levels ( 32203549) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Medication use (anti-inflammatory and antirheumatic products, non-steroids) ( 31015401) Neuroticism ( 29255261) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Schizophrenia ( 21926974 22883433 30285260) Squamous cell lung carcinoma ( 28604730) Triglyceride levels ( 32203549)
Interacting Genes		27 interacting genes: BEND7 BIVM EPN2 EPN3 INCA1 IRF3 LMNA MACROH2A1 MAGEA6 MIR138-2 MIR18B MNAT1 OTUB2 PHF7 RABEP1 RNF10 RNF126 SUMO2 THAP1 TLE5 TRIM41 UBE2D1 UBE2D2 UBE2D3 USP36 USP39 USP5	11 interacting genes: DAZAP2 FAM168A LAPTM5 LITAF MID1 NTAQ1 RNF11 RNF8 RPS27A TRIM26 UBC
Entrez ID		7726	55040
HPRD ID		02901	06272
Ensembl ID		ENSG00000234127	ENSG00000049283
Uniprot IDs		A0A024RCP3 Q12899	Q9H201
PDB IDs
Enriched GO Terms of Interacting Partners?
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