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MIR34A and SART3
Data Source:
BioGRID
(unspecified method)
MIR34A
SART3
Description
microRNA 34a
spliceosome associated factor 3, U4/U6 recycling protein
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Exosome
Extracellular Vesicle
Nucleus
Nucleoplasm
U6atac SnRNP
Cytoplasm
Cajal Body
Nuclear Speck
U4/U6 X U5 Tri-snRNP Complex
ASAP Complex
U4/U6 SnRNP
U4atac/U6atac SnRNP
Molecular Function
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
RNA Binding
Protein Binding
U6 SnRNA Binding
U4 SnRNA Binding
U6atac SnRNA Binding
Histone Binding
Ubiquitin-specific Protease Binding
Biological Process
Cellular Response To DNA Damage Stimulus
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Positive Regulation Of Lipid Storage
Positive Regulation Of Cell Death
Negative Regulation Of Angiogenesis
Negative Regulation Of Cell Migration
Tumor Necrosis Factor-mediated Signaling Pathway
Gene Silencing By MiRNA
Negative Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway
Cholesterol Homeostasis
Response To Axon Injury
Negative Regulation Of B Cell Receptor Signaling Pathway
Positive Regulation Of Smooth Muscle Cell Differentiation
Negative Regulation Of Protein Kinase B Signaling
Negative Regulation Of Vascular Wound Healing
Triglyceride Homeostasis
Positive Regulation Of Cell Cycle Arrest
Cellular Response To Hypoxia
Negative Regulation Of Smooth Muscle Cell Chemotaxis
Negative Regulation Of Protein Serine/threonine Kinase Activity
Negative Regulation Of Calcium Ion Import
Positive Regulation Of Blood Vessel Endothelial Cell Differentiation
Negative Regulation Of Lipid Transporter Activity
Negative Regulation Of Amyloid-beta Clearance
Positive Regulation Of Protein Acetylation
Negative Regulation Of Intracellular Signal Transduction
Negative Regulation Of Sprouting Angiogenesis
Negative Regulation Of Vascular Endothelial Growth Factor Production
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration
Positive Regulation Of Connective Tissue Replacement
Positive Regulation Of Hydrogen Peroxide-induced Cell Death
Negative Regulation Of Vascular Endothelial Cell Proliferation
Positive Regulation Of Cellular Senescence
Spliceosomal Tri-snRNP Complex Assembly
Spliceosomal SnRNP Assembly
MRNA Splicing, Via Spliceosome
Nucleosome Assembly
Regulation Of Gene Expression
Positive Regulation Of Histone Deubiquitination
Pathways
Drugs
Diseases
Disseminated superficial actinic porokeratosis (DSAP)
GWAS
Height (
31562340
)
Lean body mass (
28552196
)
Acne (severe) (
24927181
)
Interacting Genes
102 interacting genes:
ADARB1
AIMP1
AIMP2
APOBEC3B
AQR
ATXN2L
C1QBP
CDC5L
CELF1
CPSF1
CPSF6
DARS1
DDX1
DDX21
DDX3X
DDX3Y
DHX36
DHX37
EDC4
EIF2AK2
EPRS1
ESRP1
FAM98A
FAM98B
FIP1L1
FUS
G3BP2
HARS2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
MYEF2
NOL6
NONO
NUDT16L1
NUDT21
NUFIP2
PDCD11
PGAM5
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
PUM1
PURA
QARS1
RARS1
RBFOX2
RBM12B
RBM14
RBM4
RTCB
SART3
SF1
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SYMPK
SYNCRIP
TAF15
TIAL1
TRA2A
TRA2B
TRIM25
TRMT1L
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZNF346
29 interacting genes:
AR
C6
COIL
H2AC20
H2BC21
KPNA2
LSM7
MEGF10
MIR1-1
MIR128-2
MIR143
MIR18A
MIR18B
MIR19B2
MIR200B
MIR200C
MIR221
MIR34A
MIR34B
MIR7-1
MIR7-3
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
PRPF3
RNPS1
ZNF620
ZNF71
Entrez ID
407040
9733
HPRD ID
11532
Ensembl ID
ENSG00000284357
ENSG00000075856
Uniprot IDs
A0A499FI31
Q15020
PDB IDs
2DO4
5CTQ
5CTR
5CTT
5JJW
5JJX
5JPZ
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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