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MIR34A and PUM1
Data Source:
BioGRID
(unspecified method)
MIR34A
PUM1
Description
microRNA 34a
pumilio RNA binding family member 1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Exosome
Extracellular Vesicle
P-body
Nucleoplasm
Cytoplasm
Cytosol
Cytoplasmic Stress Granule
Molecular Function
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
RNA Binding
MRNA Binding
MRNA 3'-UTR Binding
Protein Binding
MiRNA Binding
Biological Process
Cellular Response To DNA Damage Stimulus
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Positive Regulation Of Lipid Storage
Positive Regulation Of Cell Death
Negative Regulation Of Angiogenesis
Negative Regulation Of Cell Migration
Tumor Necrosis Factor-mediated Signaling Pathway
Gene Silencing By MiRNA
Negative Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway
Cholesterol Homeostasis
Response To Axon Injury
Negative Regulation Of B Cell Receptor Signaling Pathway
Positive Regulation Of Smooth Muscle Cell Differentiation
Negative Regulation Of Protein Kinase B Signaling
Negative Regulation Of Vascular Wound Healing
Triglyceride Homeostasis
Positive Regulation Of Cell Cycle Arrest
Cellular Response To Hypoxia
Negative Regulation Of Smooth Muscle Cell Chemotaxis
Negative Regulation Of Protein Serine/threonine Kinase Activity
Negative Regulation Of Calcium Ion Import
Positive Regulation Of Blood Vessel Endothelial Cell Differentiation
Negative Regulation Of Lipid Transporter Activity
Negative Regulation Of Amyloid-beta Clearance
Positive Regulation Of Protein Acetylation
Negative Regulation Of Intracellular Signal Transduction
Negative Regulation Of Sprouting Angiogenesis
Negative Regulation Of Vascular Endothelial Growth Factor Production
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration
Positive Regulation Of Connective Tissue Replacement
Positive Regulation Of Hydrogen Peroxide-induced Cell Death
Negative Regulation Of Vascular Endothelial Cell Proliferation
Positive Regulation Of Cellular Senescence
Spermatogenesis
Adult Locomotory Behavior
Posttranscriptional Regulation Of Gene Expression
Posttranscriptional Gene Silencing
Production Of MiRNAs Involved In Gene Silencing By MiRNA
Regulation Of MRNA Stability
Stem Cell Differentiation
Regulation Of Cell Cycle
Regulation Of Chromosome Segregation
Regulation Of Gene Silencing By MiRNA
MRNA Destabilization
Positive Regulation Of RIG-I Signaling Pathway
Positive Regulation Of Gene Silencing By MiRNA
Pathways
Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS
Height (
31562340
)
Lean body mass (
28552196
)
Interacting Genes
102 interacting genes:
ADARB1
AIMP1
AIMP2
APOBEC3B
AQR
ATXN2L
C1QBP
CDC5L
CELF1
CPSF1
CPSF6
DARS1
DDX1
DDX21
DDX3X
DDX3Y
DHX36
DHX37
EDC4
EIF2AK2
EPRS1
ESRP1
FAM98A
FAM98B
FIP1L1
FUS
G3BP2
HARS2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
MYEF2
NOL6
NONO
NUDT16L1
NUDT21
NUFIP2
PDCD11
PGAM5
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
PUM1
PURA
QARS1
RARS1
RBFOX2
RBM12B
RBM14
RBM4
RTCB
SART3
SF1
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SYMPK
SYNCRIP
TAF15
TIAL1
TRA2A
TRA2B
TRIM25
TRMT1L
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZNF346
47 interacting genes:
ATXN1
EIF5
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR143
MIR145
MIR15B
MIR17
MIR18B
MIR199A1
MIR199A2
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR25
MIR29A
MIR29C
MIR34A
MIR7-1
MIR9-3
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
PRR12
SMAD1
Entrez ID
407040
9698
HPRD ID
06230
Ensembl ID
ENSG00000284357
ENSG00000134644
Uniprot IDs
Q14671
PDB IDs
1IB2
1M8W
1M8X
1M8Y
1M8Z
2YJY
3BSB
3BSX
3Q0L
3Q0M
3Q0N
3Q0O
3Q0P
5YKH
5YKI
Enriched GO Terms of Interacting Partners
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