SART3 and RNPS1

Data Source:
BioGRID (affinity chromatography technology, two hybrid)
HPRD (in vitro, two hybrid, in vivo)

		SART3	RNPS1
Description		spliceosome associated factor 3, U4/U6 recycling protein	RNA binding protein with serine rich domain 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm U6atac SnRNP Cytoplasm Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex ASAP Complex U4/U6 SnRNP U4atac/U6atac SnRNP	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Exon-exon Junction Complex ASAP Complex
	Molecular Function	RNA Binding Protein Binding U6 SnRNA Binding U4 SnRNA Binding U6atac SnRNA Binding Histone Binding Ubiquitin-specific Protease Binding	RNA Binding MRNA 3'-UTR Binding Protein Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Nucleosome Assembly Regulation Of Gene Expression Positive Regulation Of Histone Deubiquitination	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Transcription, DNA-templated RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Positive Regulation Of Apoptotic Process Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases		Disseminated superficial actinic porokeratosis (DSAP)
GWAS		Acne (severe) ( 24927181)
Interacting Genes		29 interacting genes: AR C6 COIL H2AC20 H2BC21 KPNA2 LSM7 MEGF10 MIR1-1 MIR128-2 MIR143 MIR18A MIR18B MIR19B2 MIR200B MIR200C MIR221 MIR34A MIR34B MIR7-1 MIR7-3 MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 PRPF3 RNPS1 ZNF620 ZNF71	62 interacting genes: ABI2 CCNL1 CHERP CLK2 CLK3 DVL2 ELOA2 FAM81B GOLGA6L9 GPATCH8 HEXIM2 HOXD4 LUC7L3 NKAPD1 NKTR PICK1 PIN1 PNN PRPF38A PSTPIP1 RBM8A RBMY1F RBMY1J SAP18 SART3 SDCBP2 SRP54 SRPK1 SRPK2 SRRM4 SRSF1 SRSF10 SRSF11 SRSF3 SRSF4 SRSF6 SRSF7 SRSF9 STX11 TAF2 TBC1D26 TRA2A TRA2B TRIM41 U2AF1 UBQLN4 UPF2 USP4 YTHDC1 YWHAB YWHAG ZBTB14 ZNF165 ZNF286A ZNF345 ZNF394 ZNF41 ZNF473 ZNF490 ZNF660 ZRANB1 ZSCAN30
Entrez ID		9733	10921
HPRD ID		11532	07341
Ensembl ID		ENSG00000075856	ENSG00000205937
Uniprot IDs		A0A499FI31 Q15020	D3DU92 H3BMS0 Q15287
PDB IDs		2DO4 5CTQ 5CTR 5CTT 5JJW 5JJX 5JPZ	4A8X
Enriched GO Terms of Interacting Partners?
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