KRT72 and KRT16

Data Source:
BioGRID (two hybrid)

		KRT72	KRT16
Description		keratin 72	keratin 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament Extracellular Exosome	Nucleus Cytosol Cytoskeleton Intermediate Filament Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding
	Biological Process	Biological_process Keratinization Cornification	Morphogenesis Of An Epithelium Inflammatory Response Cytoskeleton Organization Aging Keratinocyte Differentiation Negative Regulation Of Cell Migration Keratinization Hair Cycle Innate Immune Response Intermediate Filament Cytoskeleton Organization Keratinocyte Migration Establishment Of Skin Barrier Cornification
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs			Zinc Zinc acetate
Diseases			Non-epidermolytic palmoplantar keratoderma (NEPPK) Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS		High density lipoprotein cholesterol levels ( 30498476)
Interacting Genes		19 interacting genes: BLOC1S6 HSPB1 KRT13 KRT14 KRT15 KRT16 KRT17 KRT18 KRT19 KRT20 KRT24 KRT25 KRT27 KRT31 KRT32 KRT33B KRT35 KRT38 KRT40	56 interacting genes: AMOT ARFIP2 C1orf109 C1orf216 CARD9 CCDC146 CCDC17 CCHCR1 CCNC CDK18 CYTH4 EPM2AIP1 GAS8 GNG10 HGS KIFC3 KLC4 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6C KRT71 KRT72 KRT73 KRT74 KRT76 KRT78 KRT79 KRT8 KRT80 KRT81 KRT83 KRT85 KRT86 LMO1 LNX1 MBD3 PKN1 POLL PPP1R18 PRKAA2 PRPH PUS10 SEMA4C SGF29 SMARCD1 SMARCE1 SNAPIN TCHP TSG101 TTC23 TXLNB USHBP1
Entrez ID		140807	3868
HPRD ID		09746	01018
Ensembl ID		ENSG00000170486	ENSG00000186832
Uniprot IDs		Q14CN4	P08779
PDB IDs
Enriched GO Terms of Interacting Partners?
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