ITGAD and ICAM3

Data Source:
HPRD (in vitro)

		ITGAD	ICAM3
Description		integrin subunit alpha D	intercellular adhesion molecule 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integrin Complex Cell Surface	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	Metal Ion Binding	Signaling Receptor Binding Integrin Binding Protein Binding
	Biological Process	Immune Response Integrin-mediated Signaling Pathway Extracellular Matrix Organization Heterotypic Cell-cell Adhesion	Stimulatory C-type Lectin Receptor Signaling Pathway Phagocytosis Cell Adhesion Extracellular Matrix Organization Regulation Of Immune Response Cell-cell Adhesion
Pathways		Integrin cell surface interactions	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions CD209 (DC-SIGN) signaling
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 27863252) Platelet count ( 32888494) Plateletcrit ( 32888494) Red cell distribution width ( 32888494 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Crohn's disease ( 28067908 21102463) Inflammatory bowel disease ( 28067908) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031)
Interacting Genes		4 interacting genes: ICAM3 ITGB2 SHARPIN VCAM1	20 interacting genes: APP BRICD5 CD209 CLDN19 CLDN4 CLEC4M EDDM3B EZR ITGAD ITGAL ITGB2 MSN NINJ2 PRKCQ SEC22A SFTPC SMCO4 SMIM1 TSPO ZBTB16
Entrez ID		3681	3385
HPRD ID		11785	00889
Ensembl ID		ENSG00000156886	ENSG00000076662
Uniprot IDs		Q13349 Q59H14	A0A024R7C1 K7ERN2 P32942
PDB IDs			1T0P
Enriched GO Terms of Interacting Partners?
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