DPPA3 and IPO5

Data Source:
HPRD (in vivo, in vitro)

		DPPA3	IPO5
Description		developmental pluripotency associated 3	importin 5
Image		No pdb structure
GO Annotations	Cellular Component	Female Pronucleus Male Pronucleus Nucleus Cytoplasm	Nucleus Nuclear Pore Nucleolus Cytoplasm Membrane
	Molecular Function	Protein Binding Methylated Histone Binding	RNA Binding GTPase Inhibitor Activity Protein Binding Nuclear Localization Sequence Binding Small GTPase Binding Nuclear Import Signal Receptor Activity
	Biological Process	Chromatin Organization Protection Of DNA Demethylation Of Female Pronucleus Negative Regulation Of DNA Demethylation Regulation Of Genetic Imprinting	Protein Import Into Nucleus NLS-bearing Protein Import Into Nucleus Ribosomal Protein Import Into Nucleus Viral Process Negative Regulation Of GTPase Activity Positive Regulation Of Protein Import Into Nucleus Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cellular Response To Amino Acid Stimulus
Pathways			vRNP Assembly
Drugs
Diseases
GWAS		Borderline personality disorder ( 28632202) White matter hyperintensities in ischemic stroke ( 26674333)	Peripheral artery disease ( 26488411) Smooth-surface caries ( 24556642)
Interacting Genes		14 interacting genes: DEPDC5 DYNLL1 DYNLL2 HAUS7 IPO5 KRT27 KRT76 NUP62 PLEKHG4 SERTAD3 SYCE1L TFIP11 TRIB3 ZNF618	26 interacting genes: ACD BHLHB9 CAB39 CDC42 DPPA3 DTNBP1 H1-0 NUP153 NUP214 NUP62 NUP98 PTEN RAG2 RAN RANBP2 RPL13 RPL23 RPL23A RPL5 RPL7 RPS7 SRP19 SUMO2 TERF1 TINF2 WASL
Entrez ID		359787	3843
HPRD ID		16331	03597
Ensembl ID		ENSG00000187569	ENSG00000065150
Uniprot IDs		Q6W0C5	B3KWG6 O00410 Q9BVS9
PDB IDs			6XTE 6XU2
Enriched GO Terms of Interacting Partners?
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