IPO5 and DTNBP1

Data Source:
BioGRID (two hybrid)

		IPO5	DTNBP1
Description		importin 5	dystrobrevin binding protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Pore Nucleolus Cytoplasm Membrane	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Endosome Membrane Postsynaptic Density Microtubule Cytoskeleton Sarcoplasm Axon Growth Cone Midbody Synaptic Vesicle Membrane BLOC-1 Complex Melanosome Membrane Sarcolemma Neuron Projection Dendritic Spine Postsynaptic Membrane Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse Axon Cytoplasm
	Molecular Function	RNA Binding GTPase Inhibitor Activity Protein Binding Nuclear Localization Sequence Binding Small GTPase Binding Nuclear Import Signal Receptor Activity	Protein Binding
	Biological Process	Protein Import Into Nucleus NLS-bearing Protein Import Into Nucleus Ribosomal Protein Import Into Nucleus Viral Process Negative Regulation Of GTPase Activity Positive Regulation Of Protein Import Into Nucleus Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cellular Response To Amino Acid Stimulus	Positive Regulation Of Neurotransmitter Secretion Negative Regulation Of Protein Kinase Activity Blood Coagulation Anterograde Axonal Transport Positive Regulation Of Gene Expression Regulation Of Dopamine Secretion Neuron Projection Development Actin Cytoskeleton Reorganization Negative Regulation Of Protein Binding Melanosome Organization Regulation Of JUN Kinase Activity Anterograde Synaptic Vesicle Transport Neuron Projection Morphogenesis Dendrite Morphogenesis Platelet Dense Granule Organization Regulation Of Dopamine Receptor Signaling Pathway Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Synaptic Vesicle Exocytosis
Pathways		vRNP Assembly	Golgi Associated Vesicle Biogenesis
Drugs
Diseases			Hermansky-Pudlak syndrome (HPS)
GWAS		Peripheral artery disease ( 26488411) Smooth-surface caries ( 24556642)	Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Corneal astigmatism ( 30306274) Multiple myeloma ( 27363682) Squamous cell carcinoma ( 31174203)
Interacting Genes		26 interacting genes: ACD BHLHB9 CAB39 CDC42 DPPA3 DTNBP1 H1-0 NUP153 NUP214 NUP62 NUP98 PTEN RAG2 RAN RANBP2 RPL13 RPL23 RPL23A RPL5 RPL7 RPS7 SRP19 SUMO2 TERF1 TINF2 WASL	50 interacting genes: ABI3 AKAP6 ARFIP2 BICRAL BLOC1S5 BLOC1S6 BRF1 CCDC146 CCDC153 CCNA2 CCND3 CMYA5 DCTN1 DGCR6L DST DTNA DTNB ELOVL7 HAUS1 IFT20 IPO5 KALRN KANSL1 KIAA0408 KIFC3 KRT75 MACF1 NBEA NDN NECAB2 NUF2 OIP5 P4HA3 PSME3 RAB11A RBSN SDCBP SFR1 SHFL SNAPIN SRGAP3 SSC5D SYNE1 TRAF3IP1 TRIM2 TRIM27 TRIM9 VRK2 WASHC3 ZNF490
Entrez ID		3843	84062
HPRD ID		03597	06190
Ensembl ID		ENSG00000065150	ENSG00000047579
Uniprot IDs		B3KWG6 O00410 Q9BVS9	A0A087WYP9 A0A0S2Z5U8 A6NFV8 D6RJC6 Q96EV8
PDB IDs		6XTE 6XU2
Enriched GO Terms of Interacting Partners?
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