DPPA3 and HAUS7

Data Source:
BioGRID (two hybrid)

		DPPA3	HAUS7
Description		developmental pluripotency associated 3	HAUS augmin like complex subunit 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Female Pronucleus Male Pronucleus Nucleus Cytoplasm	Centrosome Cytosol HAUS Complex Mitotic Spindle Microtubule
	Molecular Function	Protein Binding Methylated Histone Binding	Protein Binding Thioesterase Binding Microtubule Minus-end Binding
	Biological Process	Chromatin Organization Protection Of DNA Demethylation Of Female Pronucleus Negative Regulation Of DNA Demethylation Regulation Of Genetic Imprinting	G2/M Transition Of Mitotic Cell Cycle Centrosome Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Spindle Assembly Cell Division Ciliary Basal Body-plasma Membrane Docking
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Borderline personality disorder ( 28632202) White matter hyperintensities in ischemic stroke ( 26674333)
Interacting Genes		14 interacting genes: DEPDC5 DYNLL1 DYNLL2 HAUS7 IPO5 KRT27 KRT76 NUP62 PLEKHG4 SERTAD3 SYCE1L TFIP11 TRIB3 ZNF618	3 interacting genes: ATF4 DPPA3 UCHL5
Entrez ID		359787	55559
HPRD ID		16331	18695
Ensembl ID		ENSG00000187569	ENSG00000213397
Uniprot IDs		Q6W0C5	Q99871
PDB IDs
Enriched GO Terms of Interacting Partners?
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