HTR6 and CHN1

Data Source:
BioGRID (two hybrid)

		HTR6	CHN1
Description		5-hydroxytryptamine receptor 6	chimerin 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cilium Dendrite Synapse	Cytosol
	Molecular Function	Histamine Receptor Activity G Protein-coupled Serotonin Receptor Activity Protein Binding Neurotransmitter Receptor Activity	GTPase Activator Activity Protein Binding Metal Ion Binding Ephrin Receptor Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Cerebral Cortex Cell Migration Positive Regulation Of TOR Signaling G Protein-coupled Serotonin Receptor Signaling Pathway	Motor Neuron Axon Guidance Intracellular Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Ephrin Receptor Signaling Pathway Regulation Of Axonogenesis Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Serotonin receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production	Rho GTPase cycle
Drugs		Ziprasidone Amitriptyline Olanzapine Clozapine Loxapine Imipramine Chlorpromazine Haloperidol Amoxapine Paroxetine Cyclobenzaprine Ergoloid mesylate Doxepin Quetiapine Aripiprazole Chlorprothixene Dimethyltryptamine Lysergic acid diethylamide Iloperidone SGS518 PRX-07034 SUVN-502 Sertindole Mianserin Asenapine Zotepine Setiptiline Dihydroergocornine Gilteritinib Tiapride Dihydroergocristine Aripiprazole lauroxil
Diseases			Duane retraction syndrome
GWAS		Chronotype ( 26955885 27494321) Morning person ( 30696823) Morning vs. evening chronotype ( 26955885 27494321)	Post bronchodilator FEV1 ( 26634245)
Interacting Genes		31 interacting genes: ABCA2 ACTB AIP AKR1A1 AP2M1 AP4S1 ATXN10 CHN1 CMSS1 COPS5 DDRGK1 DHRS1 EIF4A3 FYN GNAQ GNAS HDGFL2 IDS MAP1B NF1 NRXN3 PARP8 RUNDC3A SCHIP1 SLC6A1 SRRT SYT5 THY1 TMEM98 TTYH1 UQCRFS1	16 interacting genes: ACVR1 ADORA2A ANKK1 BMPR1B CDK5 CDK5R1 ERBB2 GTF3C1 HEMK1 HTR6 MAPK1 MAPK8IP2 NCK2 RAC1 RPS3A TGFBR1
Entrez ID		3362	1123
HPRD ID		03066	00319
Ensembl ID		ENSG00000158748	ENSG00000128656
Uniprot IDs		P50406	P15882
PDB IDs			2OSA 3CXL
Enriched GO Terms of Interacting Partners?
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