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CHN1 and NCK2
Data Source:
BioGRID
(two hybrid)
CHN1
NCK2
Description
chimerin 1
NCK adaptor protein 2
Image
GO Annotations
Cellular Component
Cytosol
Cytoplasm
Endoplasmic Reticulum
Cytosol
Vesicle Membrane
Postsynaptic Density
Molecular Function
GTPase Activator Activity
Protein Binding
Metal Ion Binding
Ephrin Receptor Binding
Phosphotyrosine Residue Binding
Protein Binding
Cytoskeletal Anchor Activity
Signaling Receptor Complex Adaptor Activity
Signaling Adaptor Activity
Protein-containing Complex Binding
Scaffold Protein Binding
Biological Process
Motor Neuron Axon Guidance
Intracellular Signal Transduction
Regulation Of GTPase Activity
Positive Regulation Of GTPase Activity
Ephrin Receptor Signaling Pathway
Regulation Of Axonogenesis
Regulation Of Small GTPase Mediated Signal Transduction
Immunological Synapse Formation
Actin Filament Organization
Signal Transduction
Signal Complex Assembly
Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Negative Regulation Of Cell Population Proliferation
Cell Migration
Lamellipodium Assembly
Positive Regulation Of Actin Filament Polymerization
Negative Regulation Of Peptidyl-serine Phosphorylation
Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress
Positive Regulation Of T Cell Proliferation
T Cell Activation
Positive Regulation Of Transcription By RNA Polymerase II
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Ephrin Receptor Signaling Pathway
Dendritic Spine Development
Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of PERK-mediated Unfolded Protein Response
Negative Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Pathways
Rho GTPase cycle
Downstream signal transduction
Nephrin family interactions
Ephrin signaling
Activation of RAC1
VEGFA-VEGFR2 Pathway
Regulation of cortical dendrite branching
Drugs
Diseases
Duane retraction syndrome
GWAS
Post bronchodilator FEV1 (
26634245
)
Addiction (
23533358
)
Anti-chlamydia trachomatis IgG seropositivity (
33204752
)
Mean platelet volume (
32888494
)
Platelet distribution width (
32888494
27863252
)
Systolic blood pressure in sickle cell anemia (
24058526
)
Interacting Genes
16 interacting genes:
ACVR1
ADORA2A
ANKK1
BMPR1B
CDK5
CDK5R1
ERBB2
GTF3C1
HEMK1
HTR6
MAPK1
MAPK8IP2
NCK2
RAC1
RPS3A
TGFBR1
171 interacting genes:
ABI1
ABI2
ABI3
ANKRD55
ANKS1B
ARHGAP32
ATN1
AXIN1
AXL
BCAR1
BCL11A
BTG1
C4orf17
CBARP
CBLB
CCDC120
CCDC33
CD3E
CHN1
CHN2
CIB1
CIPC
CLEC17A
CPSF6
CPSF7
CUEDC1
DDR1
DEFB124
DISC1
DLGAP4
DNM1
DOCK1
DOK1
DRAP1
DTX3
DVL1
EEF1G
EFHC2
EFNB1
EFNB2
EFS
EGFR
EIF3H
ERBB2
ERBB3
ERBB4
FAM124A
FAM47A
FAM53C
FAM83A
FASLG
FBXL19
FCRL2
FGFR1
FOSB
FXR2
FYB1
GAB1
GAREM1
GGN
HNRNPK
HOMEZ
HOXA1
HOXC4
HOXD8
HSF2BP
ILK
INCA1
INTS2
IRS1
KCTD17
KHDRBS1
KIAA0408
KIAA1217
KIT
KLHL24
KLHL35
KPRP
LCP2
LIMS1
LNX1
LRRIQ3
LZTS2
MAGEA6
MASP1
MBD6
MEOX2
MET
MIA3
MNT
MYPOP
NCKIPSD
NELFA
NET1
NFKBID
NHSL2
NPAS2
NPHS1
NR5A1
NTRK2
NUTM2F
ONECUT3
PAK1
PAK2
PBX4
PDGFRB
PHETA1
PIK3AP1
PKD1
PKN2
PRDM6
PRR16
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PSMD10
PTK2
RASSF7
RBBP8NL
RBM26
REEP4
REL
SCML2
SCX
SF1
SF3A2
SF3B4
SHD
SKAP2
SMARCB1
SNW1
SOCS7
SORBS2
SOS1
SPATA2L
SPATC1L
SPRY2
SRMS
SRPK1
SRPK2
SSH3
SYNGAP1
SYNPO
TCF4
TCP10L
TMEM121
TNR
TRIM27
TRIM41
TRIP6
TXK
UBC
USP32
VARS2
VPS37B
WAS
WASF1
WASL
WBP11
WIPF1
WIPF2
ZBTB12
ZBTB42
ZBTB7B
ZC2HC1A
ZC2HC1B
ZNF341
ZNF526
ZNF688
Entrez ID
1123
8440
HPRD ID
00319
05378
Ensembl ID
ENSG00000128656
ENSG00000071051
Uniprot IDs
P15882
A0A0S2Z4M6
E7ERP6
O43639
PDB IDs
2OSA
3CXL
1U5S
1WX6
1Z3K
2B86
2CIA
2FRW
2FRY
2JXB
4E6R
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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