HTR6 and HDGFL2

Data Source:
BioGRID (two hybrid)

		HTR6	HDGFL2
Description		5-hydroxytryptamine receptor 6	HDGF like 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cilium Dendrite Synapse	Nucleus
	Molecular Function	Histamine Receptor Activity G Protein-coupled Serotonin Receptor Activity Protein Binding Neurotransmitter Receptor Activity	Double-stranded DNA Binding Transcription Coregulator Activity Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Cerebral Cortex Cell Migration Positive Regulation Of TOR Signaling G Protein-coupled Serotonin Receptor Signaling Pathway	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Growth
Pathways		Serotonin receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs		Ziprasidone Amitriptyline Olanzapine Clozapine Loxapine Imipramine Chlorpromazine Haloperidol Amoxapine Paroxetine Cyclobenzaprine Ergoloid mesylate Doxepin Quetiapine Aripiprazole Chlorprothixene Dimethyltryptamine Lysergic acid diethylamide Iloperidone SGS518 PRX-07034 SUVN-502 Sertindole Mianserin Asenapine Zotepine Setiptiline Dihydroergocornine Gilteritinib Tiapride Dihydroergocristine Aripiprazole lauroxil
Diseases
GWAS		Chronotype ( 26955885 27494321) Morning person ( 30696823) Morning vs. evening chronotype ( 26955885 27494321)
Interacting Genes		31 interacting genes: ABCA2 ACTB AIP AKR1A1 AP2M1 AP4S1 ATXN10 CHN1 CMSS1 COPS5 DDRGK1 DHRS1 EIF4A3 FYN GNAQ GNAS HDGFL2 IDS MAP1B NF1 NRXN3 PARP8 RUNDC3A SCHIP1 SLC6A1 SRRT SYT5 THY1 TMEM98 TTYH1 UQCRFS1	7 interacting genes: AGTR1 CSNK2A1 H3C14 HTR2B HTR6 TERF1 TERF2
Entrez ID		3362	84717
HPRD ID		03066	13639
Ensembl ID		ENSG00000158748	ENSG00000167674
Uniprot IDs		P50406	Q7Z4V5
PDB IDs			3EAE 3QBY 3QJ6
Enriched GO Terms of Interacting Partners?
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