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HSPB2 and PGM1
Data Source:
BioGRID
(two hybrid)
HSPB2
PGM1
Description
heat shock protein family B (small) member 2
phosphoglucomutase 1
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Extracellular Region
Cytoplasm
Cytosol
Extracellular Exosome
Tertiary Granule Lumen
Ficolin-1-rich Granule Lumen
Molecular Function
Structural Constituent Of Eye Lens
Protein Binding
Enzyme Activator Activity
Magnesium Ion Binding
Phosphoglucomutase Activity
Protein Binding
Biological Process
Response To Unfolded Protein
Regulation Of Catalytic Activity
Carbohydrate Metabolic Process
Glycogen Biosynthetic Process
Glycogen Catabolic Process
Glucose Metabolic Process
Gluconeogenesis
Glycolytic Process
Galactose Catabolic Process
Neutrophil Degranulation
Pathways
Glycogen synthesis
Defective PGM1 causes PGM1-CDG (CDG1t)
Neutrophil degranulation
Drugs
Alpha-D-Glucose 1,6-Bisphosphate
Alpha-D-Glucose-1-Phosphate-6-Vanadate
Diseases
GWAS
Alcohol consumption (transferrin glycosylation) (
21665994
)
Blood protein levels (
29875488
)
Type 1 diabetes (
32005708
19430480
)
Type 2 diabetes (
32499647
)
Interacting Genes
108 interacting genes:
A1CF
A2M
ABCC9
ABCD4
ACAA2
ACTA1
ACTB
ACTC1
ACTG1
AGAP11
ALDH2
ALDOA
ASAH1
ATP5F1A
ATP6V1E1
B2M
BAG3
BEX2
BEX4
BGN
BICRAL
C1QA
CAPZA2
CEP19
CKM
CLK4
CMYA5
CRYAA
CRYAB
CRYGC
CTSB
CTSD
CYP1B1
DCTN1
DCTN6
DDIT4
DMPK
DUSP1
EEF1A1
EIF4A2
ENKD1
ENO1
ENO3
ETFA
FHL2
FLNC
GAPDH
GARS1
HADHB
HNRNPD
HOXB9
HSPB3
HSPB8
KANK2
LGALS1
LMO1
LMO3
MAPKAPK5
MB
MCCC2
MDH1
MISP
MLF2
MT-CO1
MT-CO2
MT-CO3
MYBPC3
MYH6
MYOM2
MYOZ2
NARS1
NDUFA13
NDUFA6
NT5DC2
PARVA
PATZ1
PGM1
PKP2
POGZ
PPM1K
PRR35
RFPL3
RPL11
RPL36A
RPL36AL
RPS11
RPS6KA5
RYR2
SDF2
SDHA
SLC2A1
SNCA
SNU13
SNX18
TATDN1
TCAP
THEMIS2
THUMPD2
TLX3
TNNI3
TTN
TXNIP
UBL5
VEZF1
WDR1
WWOX
YPEL3
ZNF335
16 interacting genes:
APP
DNAJB6
ENO3
HSPB2
KIF1B
LINC01554
NLRP3
PAXIP1
PEA15
POT1
S100A1
S100B
TERF1
TERF2IP
TINF2
USP4
Entrez ID
3316
5236
HPRD ID
03712
01389
Ensembl ID
ENSG00000170276
ENSG00000079739
Uniprot IDs
A8KAH6
Q16082
B4DDQ8
B7Z6C2
P36871
PDB IDs
6F2R
5EPC
5F9C
5HSH
5JN5
5TR2
5VBI
5VEC
5VG7
5VIN
6SNO
6SNP
6SNQ
6UIQ
6UO6
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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